Stimulation Montage Achieves Balanced Focality and Intensity

Yushan Wang, Jonathan Brand, Wentai Liu

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation tech-nique to treat brain disorders by using a constant, low current to stimulate targeted cortex regions. Compared to the conventional tDCS that uses two large pad electrodes, multiple electrode tDCS has recently received more attention. It is able to achieve better stimulation performance in terms of stimulation intensity and focality. In this paper, we first establish a computational model of tDCS, and then propose a novel optimization algorithm using a regularization matrix λ to explore the balance between stimulation intensity and focality. The simulation study is designed such that the performance of state-of-the-art algorithms and the proposed algorithm can be compared via quantitative evaluation. The results show that the proposed algorithm not only achieves desired intensity, but also smaller target error and better focality. Robustness analysis indicates that the results are stable within the ranges of scalp and cerebrospinal fluid (CSF) conductivities, while the skull conductivity is most sensitive and should be carefully considered in real clinical applications.

Original languageEnglish
Article number169
JournalAlgorithms
Volume15
Issue number5
DOIs
Publication statusPublished - 2022 May

All Science Journal Classification (ASJC) codes

  • Theoretical Computer Science
  • Numerical Analysis
  • Computational Theory and Mathematics
  • Computational Mathematics

Fingerprint

Dive into the research topics of 'Stimulation Montage Achieves Balanced Focality and Intensity'. Together they form a unique fingerprint.

Cite this