Striatal dopamine D2/D3 receptor availability in male smokers

Yen Kuang Yang; Wei Jen Yao; Joseph P. McEvoy; Ching Lin Chu; I. Hui Lee; Po See Chen; Tzung Lieh Yeh; Nan Tsing Chiu

doi:10.1016/j.pscychresns.2005.09.008

Striatal dopamine D₂/D₃ receptor availability in male smokers

Yen Kuang Yang, Wei Jen Yao, Joseph P. McEvoy, Ching Lin Chu, I. Hui Lee, Po See Chen, Tzung Lieh Yeh, Nan Tsing Chiu

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D₂/D₃ availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D₂/D₃ receptor availability was assessed by single photon emission computed tomography with [ ¹²³]IBZM Iodo-benzaimide. There was no significant difference in striatal D₂/D₃ receptor availability between smokers and controls.

Original language	English
Pages (from-to)	87-90
Number of pages	4
Journal	Psychiatry Research - Neuroimaging
Volume	146
Issue number	1
DOIs	https://doi.org/10.1016/j.pscychresns.2005.09.008
Publication status	Published - 2006 Jan 30

All Science Journal Classification (ASJC) codes

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.pscychresns.2005.09.008

Cite this

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title = "Striatal dopamine D2/D3 receptor availability in male smokers",

abstract = "It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.",

author = "Yang, {Yen Kuang} and Yao, {Wei Jen} and McEvoy, {Joseph P.} and Chu, {Ching Lin} and Lee, {I. Hui} and Chen, {Po See} and Yeh, {Tzung Lieh} and Chiu, {Nan Tsing}",

note = "Funding Information: The work was supported by a grant from the National Science Council of Taiwan (NSC 91-2314-B-006-074). The authors thank Mitchell Chen, Shu Chuan Lin, and Linda J. Chang for their assistance in the preparation of the article.",

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AU - Yang, Yen Kuang

AU - Yao, Wei Jen

AU - McEvoy, Joseph P.

AU - Chu, Ching Lin

AU - Lee, I. Hui

AU - Chen, Po See

AU - Yeh, Tzung Lieh

AU - Chiu, Nan Tsing

N1 - Funding Information: The work was supported by a grant from the National Science Council of Taiwan (NSC 91-2314-B-006-074). The authors thank Mitchell Chen, Shu Chuan Lin, and Linda J. Chang for their assistance in the preparation of the article.

PY - 2006/1/30

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N2 - It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.

AB - It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.

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