Striatal dopamine D2/D3 receptor availability in male smokers

Yen Kuang Yang; Wei Jen Yao; Joseph P. McEvoy; Ching Lin Chu; I. Hui Lee; Po See Chen; Tzung Lieh Yeh; Nan Tsing Chiu

doi:10.1016/j.pscychresns.2005.09.008

Striatal dopamine D₂/D₃ receptor availability in male smokers

Yen Kuang Yang
, Wei Jen Yao
, Joseph P. McEvoy
, Ching Lin Chu
, I. Hui Lee
, Po See Chen
, Tzung Lieh Yeh
, Nan Tsing Chiu

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D₂/D₃ availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D₂/D₃ receptor availability was assessed by single photon emission computed tomography with [ ¹²³]IBZM Iodo-benzaimide. There was no significant difference in striatal D₂/D₃ receptor availability between smokers and controls.

Original language	English
Pages (from-to)	87-90
Number of pages	4
Journal	Psychiatry Research - Neuroimaging
Volume	146
Issue number	1
DOIs	https://doi.org/10.1016/j.pscychresns.2005.09.008
Publication status	Published - 2006 Jan 30

All Science Journal Classification (ASJC) codes

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

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10.1016/j.pscychresns.2005.09.008

Cite this

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title = "Striatal dopamine D2/D3 receptor availability in male smokers",

abstract = "It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.",

author = "Yang, \{Yen Kuang\} and Yao, \{Wei Jen\} and McEvoy, \{Joseph P.\} and Chu, \{Ching Lin\} and Lee, \{I. Hui\} and Chen, \{Po See\} and Yeh, \{Tzung Lieh\} and Chiu, \{Nan Tsing\}",

note = "Funding Information: The work was supported by a grant from the National Science Council of Taiwan (NSC 91-2314-B-006-074). The authors thank Mitchell Chen, Shu Chuan Lin, and Linda J. Chang for their assistance in the preparation of the article.",

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doi = "10.1016/j.pscychresns.2005.09.008",

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AU - Yang, Yen Kuang

AU - Yao, Wei Jen

AU - McEvoy, Joseph P.

AU - Chu, Ching Lin

AU - Lee, I. Hui

AU - Chen, Po See

AU - Yeh, Tzung Lieh

AU - Chiu, Nan Tsing

N1 - Funding Information: The work was supported by a grant from the National Science Council of Taiwan (NSC 91-2314-B-006-074). The authors thank Mitchell Chen, Shu Chuan Lin, and Linda J. Chang for their assistance in the preparation of the article.

PY - 2006/1/30

Y1 - 2006/1/30

N2 - It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.

AB - It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.

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IS - 1

ER -

Striatal dopamine D₂/D₃ receptor availability in male smokers

Abstract

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