TY - JOUR
T1 - Structural Elucidation of Murrafolines, Six Novel Binary Carbazole Alkaloids Isolated from Murraya euchrestifolia
AU - Furukawa, Hiroshi
AU - Ito, Chihiro
AU - Wu, Tian Shung
AU - McPhail, Andrew T.
PY - 1993
Y1 - 1993
N2 - In previous studies on the chemical constituents of Murraya euchrestifolia hayata(Rutaceae) collected in Taiwan, we preliminarily reported the first isolation and structure of a binary carbazole alkaloid, murrafoline-A (1). Since then, the isolation and spectroscopic structural elucidation of three new binary carbazoles, murrafoline-B (2), -C (5), and -D (3), have been reported. This paper describes in detail the structural elucidation of these novel binary carbazole alkaloids and also introduces two additional ones, murrafoline-G (4) and -H (6). Treatment of a mixture of girinimbine (7) and murrayafoline-A (8), which are monomeric carbazoles and structural components of murrafolines, with Nafion 117, an acidic perfluorinated ion-exchange resin, was found to produce murrafoline-D (3), -G (4), and -H (6).
AB - In previous studies on the chemical constituents of Murraya euchrestifolia hayata(Rutaceae) collected in Taiwan, we preliminarily reported the first isolation and structure of a binary carbazole alkaloid, murrafoline-A (1). Since then, the isolation and spectroscopic structural elucidation of three new binary carbazoles, murrafoline-B (2), -C (5), and -D (3), have been reported. This paper describes in detail the structural elucidation of these novel binary carbazole alkaloids and also introduces two additional ones, murrafoline-G (4) and -H (6). Treatment of a mixture of girinimbine (7) and murrayafoline-A (8), which are monomeric carbazoles and structural components of murrafolines, with Nafion 117, an acidic perfluorinated ion-exchange resin, was found to produce murrafoline-D (3), -G (4), and -H (6).
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U2 - 10.1248/cpb.41.1249
DO - 10.1248/cpb.41.1249
M3 - Article
AN - SCOPUS:0027249124
SN - 0009-2363
VL - 41
SP - 1249
EP - 1254
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 7
ER -