Studies of PET nonwovens modified by novel antimicrobials configured with both N-halamine and dual quaternary ammonium with different alkyl chain length

Hsiu Wen Chien, Ying Yuan Chen, Yen Lun Chen, Chi Hui Cheng, Jui-Che Lin

Research output: Contribution to journalArticle

Abstract

This work describes the synthesis of novel antimicrobial agents consisting of N-halamine and dual quaternary ammonium with different alkyl chain lengths and their antimicrobial applications for PET nonwovens. The antimicrobial agents were grafted onto PET nonwovens via esterification with a crosslinker, 1,2,3,4-butanetetracarboxylic acid (BTCA). The cyclic amide structure in the antimicrobial agents could be easily converted to N-halamine after immersion in a diluted chlorine bleach solution. Variations in surface chemical composition of the modified PET nonwovens were examined by XPS. Antimicrobial activities of the nonwovens/fabrics were tested against S. aureus (Gram-positive) and E. coli (Gram-negative) strains. Systematic investigation showed the antibacterial activities were dependent upon the alkyl chain length. The synergism of N-halamine and dual quaternary ammonium could lead to significant antimicrobial activity with inactivation of up to 90% of S. aureus and E. coli after 10 minute contact. This work suggested that the novel composite biocides with N-halamine and dual quaternary ammonium groups and the associated surface modification methods could be of use for further developing antimicrobial nonwoven applications.

Original languageEnglish
Pages (from-to)7257-7265
Number of pages9
JournalRSC Advances
Volume9
Issue number13
DOIs
Publication statusPublished - 2019 Jan 1

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Antimicrobial agents
Anti-Infective Agents
Chain length
Ammonium Compounds
Escherichia coli
Biocides
Nonwoven fabrics
Disinfectants
Chlorine
Esterification
Amides
Surface treatment
X ray photoelectron spectroscopy
Acids
Composite materials
Chemical analysis

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

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title = "Studies of PET nonwovens modified by novel antimicrobials configured with both N-halamine and dual quaternary ammonium with different alkyl chain length",
abstract = "This work describes the synthesis of novel antimicrobial agents consisting of N-halamine and dual quaternary ammonium with different alkyl chain lengths and their antimicrobial applications for PET nonwovens. The antimicrobial agents were grafted onto PET nonwovens via esterification with a crosslinker, 1,2,3,4-butanetetracarboxylic acid (BTCA). The cyclic amide structure in the antimicrobial agents could be easily converted to N-halamine after immersion in a diluted chlorine bleach solution. Variations in surface chemical composition of the modified PET nonwovens were examined by XPS. Antimicrobial activities of the nonwovens/fabrics were tested against S. aureus (Gram-positive) and E. coli (Gram-negative) strains. Systematic investigation showed the antibacterial activities were dependent upon the alkyl chain length. The synergism of N-halamine and dual quaternary ammonium could lead to significant antimicrobial activity with inactivation of up to 90{\%} of S. aureus and E. coli after 10 minute contact. This work suggested that the novel composite biocides with N-halamine and dual quaternary ammonium groups and the associated surface modification methods could be of use for further developing antimicrobial nonwoven applications.",
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Studies of PET nonwovens modified by novel antimicrobials configured with both N-halamine and dual quaternary ammonium with different alkyl chain length. / Chien, Hsiu Wen; Chen, Ying Yuan; Chen, Yen Lun; Cheng, Chi Hui; Lin, Jui-Che.

In: RSC Advances, Vol. 9, No. 13, 01.01.2019, p. 7257-7265.

Research output: Contribution to journalArticle

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