Study of morphologies and compositions of wear debris generated from peri-prostheses and a cup-on-ball simulator

Jiunn-Der Liao, Y. C. Lai, W. E. Yang, Y. C. Chiu, M. C. Wang

Research output: Contribution to journalArticlepeer-review


This study approaches to predict factors leading to failure of hip joint prosthesis. In particular, wear-associated debris probably provokes bone tissue resorption and relative diversity in mechanical properties at the articulating surfaces, which also cause different degrees of wear. This work assumes an accelerated condition for a cup-on-ball simulator, tried to interpret the occurrence of wear debris generation and collected the released species. Wear species are characterized by estimating the released sequences, morphologies and by doing qualitative and quantitative analyses. Experimental results were also compared with tissue-detached particles obtained from peri-prosthesis. Scanning Electron Microscope, Inductively Coupled Plasma Mass Spectrometer and Electron Spectroscopy for Chemical Analysis were used for identifying the tissue-detached particles, filtered samples and circulated liquid, at 300K, 600K, 1.0 M and 1.3 M testing cycles, respectively. Analytical results revealed that morphologies and concentrations of wear debris varied with testing cycles, which generated in sequence: initial agglomerates, e.g. carbonates from scissioned polyethylene in spherical foam, and then delaminated to plate-like debris. The composition likely includes: metallic oxides, carbonates and mixed compounds. Accumulation of released mass increased with the testing cycles, they showed an upward relationship, probably due to gradual delamination at the load-bearing acetabular cup. The tissue-detached particles exhibited as green-in-white and purple-in-black colors with the dimensions of ca. 1 squarem in length. The compositions were comprised of main elements from two types of the prosthetic components. The black-like particles were identified as titanium oxide-rich species. Although generations of wear species were different in running mechanics, agglomeration of micron-scale species into particles was observed. This work may provide practical data, as a reference for further osteolysis study as well as loosening evolution occurred at the articulating surfaces.

Original languageEnglish
Pages (from-to)141-150
Number of pages10
JournalChinese Journal of Medical and Biological Engineering
Issue number3
Publication statusPublished - 2000 Jan 1

All Science Journal Classification (ASJC) codes

  • Biophysics


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