Successful treatment of Kaposi's sarcoma with interferon-alpha in a patient with acquired immunodeficiency syndrome.

T. S. Yeh, C. R. Wang, W. W. Wong, G. W. Jeng, M. Y. Chen, C. Y. Liu, C. Y. Chuang, W. Y. Chen

Research output: Contribution to journalArticlepeer-review

Abstract

Although combined therapy with interferon-alpha and zidovudine may be safely administered to some patients with the acquired immunodeficiency syndrome (AIDS) and Kaposi sarcoma, no ethnic Chinese patient has been successfully treated before in this area. This case report concerns a 47-year-old male with a history of bisexuality who had suffered from oral ulcers for half a year, Human immunodeficiency virus (HIV) serology was positive, and pathology of the oral ulcers disclosed Kaposi sarcoma. Combination therapy with zidovudine and interferon-alpha was initiated. The patient received a low-dose regimen of 5.0 million U interferon-alpha s.c. per day for 8 weeks and 5 million U twice a week for another 8 weeks. The oral ulcers faded away without recurrence. This report also reviews the literatures on treatment of AIDS-related Kaposi sarcoma with interferon.

Original languageEnglish
Pages (from-to)38-43
Number of pages6
JournalZhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology
Volume26
Issue number1
Publication statusPublished - 1993 Feb

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Fingerprint Dive into the research topics of 'Successful treatment of Kaposi's sarcoma with interferon-alpha in a patient with acquired immunodeficiency syndrome.'. Together they form a unique fingerprint.

Cite this