Suction-type microfluidic immunomagnetic bead-based system for rapid detection of influenza infection

Tze Bin Huang, Lien Yu Hung, Yi Che Tsai, Chen Sheng Yeh, Huan Yao Lei, Gwo Bin Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Seasonal and novel influenza infections have caused worldwide pandemic. In order to properly treat the infected patients, a rapid and accurate influenza diagnostic tool should be developed. This study therefore presented a new integrated microfluidic system for detection of influenza infection. It integrated a suction-type, pneumatic-driven microfluidic control module, a magnetic bead-based fluorescent immunoassay (FIA) and an end-point optical detection module. This new system could successfully distinguish the influenza A and B within 15 minutes, respectively. Furthermore, the results from 40 patient specimens have concluded that 75% sensitivity and 75% specificity in both positive and negative detections. This developed system would provide a powerful platform for fast screening of influenza infection.

Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages509-511
Number of pages3
Publication statusPublished - 2011 Dec 1
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: 2011 Oct 22011 Oct 6

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume1

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period11-10-0211-10-06

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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