Syntenic assignment of dopamine tautomerase (DCT) to bovine chromosome 12

H. S. Sun, J. E. Womack, B. W. Kirkpatrick

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Abstract

Heterologous primers were used to amplify an exon and intron-containing segment of the bovine homologue of the human dopachrome tautomerase gene. After confirmation of homology by sequence analysis (exon sequence similarity greater than 90%), bovine-specific primers were developed for synteny mapping purposes. The dopachrome tautomerase gene was assigned to bovine chromosome 12 (BTA12) with 97% concordance to the coagulation factor 10 locus. Together with previous synteny mapping of bovine chromosome 12 genes, fms-related tyrosine kinase, esterase D and 5-hydroxytryptamine receptor 2, this assignment further indicates conservation between human chromosome 13q and bovine chromosome 12.

Original languageEnglish
Pages (from-to)421-422
Number of pages2
JournalAnimal Genetics
Volume27
Issue number6
Publication statusPublished - 1996 Dec 1

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology
  • Genetics

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