Synthesis and property evaluations of photocrosslinkable chitosan derivative and its photocopolymerization with poly(ethylene glycol)

Bin Hong Tsai, Chih Hsiu Lin, Jui-Che Lin

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11 Citations (Scopus)

Abstract

Photocrosslinkable polymers are clean and convenient materials for the biomedical uses. Chitosan, which owns excellent biocompatible and antimicrobial properties, is one of the choices while it is introduced with photosensitive functional groups. In this study, chitosan was N-phthaloylated to react with acryloyl chloride in the organic solvent homogeneously and the result has been verified by the solubility test. Fourier transformed infrared spectrometry and nuclear magnetic resonance spectrometer analysis indicated that the modification with the attachment of the photosensitive functional group, the acryloyl group, onto chitosan and poly(ethylene glycol) (PEG) was feasible. The differential scanning calorimetry analysis further indi cated that the melting points of the N-phathaloylated chitosan were decreased as compared with the untreated chitosan control. Then photocrosslinkable chitosan derivative (CH-PAA) was photocopolymerized with PEG diacrylate (PEGA) under UV irradiation. The adhesion strength characterization and swelling capacity evaluation for this photocopolymer have shown obvious raises of the adhesiveness and water-adsorption abilities as compared with the photopolymer of CH-PAA.

Original languageEnglish
Pages (from-to)1794-1801
Number of pages8
JournalJournal of Applied Polymer Science
Volume100
Issue number3
DOIs
Publication statusPublished - 2006 May 5

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics

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