Synthesis High Sensivity ZnO Cholesterol Biosensor with One Dimensional Nanostructures

Y. M. Lu; P. G. Jhuang; J. F. Tang; S. Y. Chu; Cw Hsu

doi:10.1088/1757-899X/131/1/012004

Synthesis High Sensivity ZnO Cholesterol Biosensor with One Dimensional Nanostructures

Y. M. Lu, P. G. Jhuang, J. F. Tang, S. Y. Chu, Cw Hsu

Research output: Contribution to journal › Conference article › peer-review

2 Citations (Scopus)

Abstract

Chelosterol ZnO biosensors were synthesized by hydrothermal method with predeposited ALD-ZnO seed layers. The ZnO nanostructures were examined by SEM, XRD, AFM, respectively. The XRD is used to analyze the crystal structures of ZnO seed layers that were grown by ALD process, then using SEM and AFM to analysis the surface morphologies of them. Growing of one dimensional ZnO nanostructures on seed layer of 10nm thickness, reveals high sensitivity of 3.15 uA (mg/dl)^-1cm^-2(121.96 uAmM^-1cm^-2) and low K_m value of 29mM in 25-100mg/dl cholesterol concentration range. The response time could be as low as 10seconds. In the study, it is found that increasing the aspect ratio of ZnO one dimensional nanostructure also increases the sensitivity and expends the linear measureable range of detecting cholesterol in solution. The thickness of seed layer has a significant influence on sensitivity for one dimensional nano ZnO cholesterol biosensor.

Original language	English
Article number	012004
Journal	IOP Conference Series: Materials Science and Engineering
Volume	131
Issue number	1
DOIs	https://doi.org/10.1088/1757-899X/131/1/012004
Publication status	Published - 2016 Jun 6
Event	4th International Conference on Manufacturing, Optimization, Industrial and Material Engineering, MOIME 2016 - Bali, Indonesia Duration: 2016 Mar 19 → 2016 Mar 20

All Science Journal Classification (ASJC) codes

Materials Science(all)
Engineering(all)

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10.1088/1757-899X/131/1/012004

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title = "Synthesis High Sensivity ZnO Cholesterol Biosensor with One Dimensional Nanostructures",

abstract = "Chelosterol ZnO biosensors were synthesized by hydrothermal method with predeposited ALD-ZnO seed layers. The ZnO nanostructures were examined by SEM, XRD, AFM, respectively. The XRD is used to analyze the crystal structures of ZnO seed layers that were grown by ALD process, then using SEM and AFM to analysis the surface morphologies of them. Growing of one dimensional ZnO nanostructures on seed layer of 10nm thickness, reveals high sensitivity of 3.15 uA (mg/dl)-1cm-2(121.96 uAmM-1cm-2) and low Km value of 29mM in 25-100mg/dl cholesterol concentration range. The response time could be as low as 10seconds. In the study, it is found that increasing the aspect ratio of ZnO one dimensional nanostructure also increases the sensitivity and expends the linear measureable range of detecting cholesterol in solution. The thickness of seed layer has a significant influence on sensitivity for one dimensional nano ZnO cholesterol biosensor.",

author = "Lu, {Y. M.} and Jhuang, {P. G.} and Tang, {J. F.} and Chu, {S. Y.} and Cw Hsu",

note = "Publisher Copyright: {\textcopyright} Published under licence by IOP Publishing Ltd.; 4th International Conference on Manufacturing, Optimization, Industrial and Material Engineering, MOIME 2016 ; Conference date: 19-03-2016 Through 20-03-2016",

year = "2016",

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doi = "10.1088/1757-899X/131/1/012004",

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T1 - Synthesis High Sensivity ZnO Cholesterol Biosensor with One Dimensional Nanostructures

AU - Lu, Y. M.

AU - Jhuang, P. G.

AU - Tang, J. F.

AU - Chu, S. Y.

AU - Hsu, Cw

N1 - Publisher Copyright: © Published under licence by IOP Publishing Ltd.

PY - 2016/6/6

Y1 - 2016/6/6

N2 - Chelosterol ZnO biosensors were synthesized by hydrothermal method with predeposited ALD-ZnO seed layers. The ZnO nanostructures were examined by SEM, XRD, AFM, respectively. The XRD is used to analyze the crystal structures of ZnO seed layers that were grown by ALD process, then using SEM and AFM to analysis the surface morphologies of them. Growing of one dimensional ZnO nanostructures on seed layer of 10nm thickness, reveals high sensitivity of 3.15 uA (mg/dl)-1cm-2(121.96 uAmM-1cm-2) and low Km value of 29mM in 25-100mg/dl cholesterol concentration range. The response time could be as low as 10seconds. In the study, it is found that increasing the aspect ratio of ZnO one dimensional nanostructure also increases the sensitivity and expends the linear measureable range of detecting cholesterol in solution. The thickness of seed layer has a significant influence on sensitivity for one dimensional nano ZnO cholesterol biosensor.

AB - Chelosterol ZnO biosensors were synthesized by hydrothermal method with predeposited ALD-ZnO seed layers. The ZnO nanostructures were examined by SEM, XRD, AFM, respectively. The XRD is used to analyze the crystal structures of ZnO seed layers that were grown by ALD process, then using SEM and AFM to analysis the surface morphologies of them. Growing of one dimensional ZnO nanostructures on seed layer of 10nm thickness, reveals high sensitivity of 3.15 uA (mg/dl)-1cm-2(121.96 uAmM-1cm-2) and low Km value of 29mM in 25-100mg/dl cholesterol concentration range. The response time could be as low as 10seconds. In the study, it is found that increasing the aspect ratio of ZnO one dimensional nanostructure also increases the sensitivity and expends the linear measureable range of detecting cholesterol in solution. The thickness of seed layer has a significant influence on sensitivity for one dimensional nano ZnO cholesterol biosensor.

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DO - 10.1088/1757-899X/131/1/012004

M3 - Conference article

AN - SCOPUS:84977275013

SN - 1757-8981

VL - 131

JO - IOP Conference Series: Materials Science and Engineering

JF - IOP Conference Series: Materials Science and Engineering

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M1 - 012004

T2 - 4th International Conference on Manufacturing, Optimization, Industrial and Material Engineering, MOIME 2016

Y2 - 19 March 2016 through 20 March 2016

ER -

Synthesis High Sensivity ZnO Cholesterol Biosensor with One Dimensional Nanostructures

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