TY - JOUR
T1 - Synthesis of silica/polypeptide hybrid nanomaterials and mesoporous silica by molecular replication of sheet-like polypeptide complexes through biomimetic mineralization
AU - Chen, Kuan Ju
AU - Chen, Hsin Ling
AU - Tang, Chen Chi
AU - Wu, Hsu Heng
AU - Jan, Jeng Shiung
N1 - Funding Information:
We acknowledge funding support from the Ministry of Science and Technology, Taiwan (MOST 107-2221-E-006-089 and 106-2221-E-006-206 ). The authors acknowledge S.S.-S. Wang for access to circular dichroism. This work was financially supported by the Hierarchical Green-Energy Materials (Hi-GEM) Research Center, from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education (MOE) and the Ministry of Science and Technology (MOST 107-3017-F-006-003) in Taiwan.
Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/4/15
Y1 - 2019/4/15
N2 - Biomimetic synthesis of silica/polymer hybrid nanomaterials inspired by silica-condensing microorganisms has gained significant advances in recent years and the as-prepared hybrid materials have been explored for a variety of applications. In this work, silica/polypeptide hybrid nanoparticles (NPs) and coating films can be facilely fabricated by silica mineralization of poly(L-lysine)-block-poly(L-threonine)/poly(L-glutamic acid) (PLL-b-PLT/PGA) fibril complexes assembled in solutions or on substrates at benign conditions. The experimental data revealed that PLL-b-PLT can self-assemble to form fibrils via intermolecular hydrogen bonding interactions between PLT chains and, upon complexing with PGA, silicas were efficiently mineralized in both the sheet-like PLL/PGA complexes and PLT domains, resulting in the fabrication of silica/polypeptide hybrid materials. After removing the polypeptides, mesoporous silicas exhibiting pore size between 2 and 10 nm and large pores (>10 nm) were fabricated by the replication of the sheet-like polypeptides and fibril complexes/aggregates, respectively. This study demonstrates that these polypeptide fibril complexes can serve both as nucleating agents and as templates for the fabrication of oxide/polypeptide hybrid NPs, mesoporous oxides and oxide/polypeptide coating films, which have potential applications in a variety of areas.
AB - Biomimetic synthesis of silica/polymer hybrid nanomaterials inspired by silica-condensing microorganisms has gained significant advances in recent years and the as-prepared hybrid materials have been explored for a variety of applications. In this work, silica/polypeptide hybrid nanoparticles (NPs) and coating films can be facilely fabricated by silica mineralization of poly(L-lysine)-block-poly(L-threonine)/poly(L-glutamic acid) (PLL-b-PLT/PGA) fibril complexes assembled in solutions or on substrates at benign conditions. The experimental data revealed that PLL-b-PLT can self-assemble to form fibrils via intermolecular hydrogen bonding interactions between PLT chains and, upon complexing with PGA, silicas were efficiently mineralized in both the sheet-like PLL/PGA complexes and PLT domains, resulting in the fabrication of silica/polypeptide hybrid materials. After removing the polypeptides, mesoporous silicas exhibiting pore size between 2 and 10 nm and large pores (>10 nm) were fabricated by the replication of the sheet-like polypeptides and fibril complexes/aggregates, respectively. This study demonstrates that these polypeptide fibril complexes can serve both as nucleating agents and as templates for the fabrication of oxide/polypeptide hybrid NPs, mesoporous oxides and oxide/polypeptide coating films, which have potential applications in a variety of areas.
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U2 - 10.1016/j.jcis.2019.02.014
DO - 10.1016/j.jcis.2019.02.014
M3 - Article
C2 - 30763891
AN - SCOPUS:85061320118
VL - 542
SP - 243
EP - 252
JO - Journal of Colloid and Interface Science
JF - Journal of Colloid and Interface Science
SN - 0021-9797
ER -