Synthesis of superparamagnetic magnetite nanoparticles for thermoresponsive drug delivery

Chia-Yu Lin, Kuo Chuan Ho

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Superparamagnetic magnetite nanoparticles (MNPs), Fe3O 4, were synthesized via the modified coprecipitation method. The morphology of these MNPs is polyhedral. The particle size of MNPs ranged from 20 to 100 nm. For combined hyperthermia and thermoresponsive drug delivery applications, the heating element, MNPs, in the core of drug carriers should increase the temperature of the target up to 43 °C under AC magnetic field. Therefore, the heating effect of these MNPs under AC magnetic field produced by a high frequency induction heater was examined. From the results, one can see that as the weight of these MNPs increased, the higher the increase in temperature was observed. Besides, the temperature increase has reached 8.7 °C in 15 min, when 20 mg MNPs were added to 2 ml water. The preliminary temperature rise suggests that it is applicable for hyperthermia and thermoresponsive drug delivery.

Original languageEnglish
Title of host publication2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Pages405-408
Number of pages4
Publication statusPublished - 2007 Aug 23
Event2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007 - Santa Clara, CA, United States
Duration: 2007 May 202007 May 24

Publication series

Name2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Volume2

Other

Other2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007
CountryUnited States
CitySanta Clara, CA
Period07-05-2007-05-24

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering

Fingerprint Dive into the research topics of 'Synthesis of superparamagnetic magnetite nanoparticles for thermoresponsive drug delivery'. Together they form a unique fingerprint.

Cite this