TY - GEN
T1 - Synthesis of superparamagnetic magnetite nanoparticles for thermoresponsive drug delivery
AU - Lin, Chia Yu
AU - Ho, Kuo Chuan
PY - 2007
Y1 - 2007
N2 - Superparamagnetic magnetite nanoparticles (MNPs), Fe3O 4, were synthesized via the modified coprecipitation method. The morphology of these MNPs is polyhedral. The particle size of MNPs ranged from 20 to 100 nm. For combined hyperthermia and thermoresponsive drug delivery applications, the heating element, MNPs, in the core of drug carriers should increase the temperature of the target up to 43 °C under AC magnetic field. Therefore, the heating effect of these MNPs under AC magnetic field produced by a high frequency induction heater was examined. From the results, one can see that as the weight of these MNPs increased, the higher the increase in temperature was observed. Besides, the temperature increase has reached 8.7 °C in 15 min, when 20 mg MNPs were added to 2 ml water. The preliminary temperature rise suggests that it is applicable for hyperthermia and thermoresponsive drug delivery.
AB - Superparamagnetic magnetite nanoparticles (MNPs), Fe3O 4, were synthesized via the modified coprecipitation method. The morphology of these MNPs is polyhedral. The particle size of MNPs ranged from 20 to 100 nm. For combined hyperthermia and thermoresponsive drug delivery applications, the heating element, MNPs, in the core of drug carriers should increase the temperature of the target up to 43 °C under AC magnetic field. Therefore, the heating effect of these MNPs under AC magnetic field produced by a high frequency induction heater was examined. From the results, one can see that as the weight of these MNPs increased, the higher the increase in temperature was observed. Besides, the temperature increase has reached 8.7 °C in 15 min, when 20 mg MNPs were added to 2 ml water. The preliminary temperature rise suggests that it is applicable for hyperthermia and thermoresponsive drug delivery.
UR - http://www.scopus.com/inward/record.url?scp=34547979568&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34547979568&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:34547979568
SN - 1420063421
SN - 9781420063424
SN - 1420061836
SN - 9781420061833
T3 - 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
SP - 405
EP - 408
BT - 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
T2 - 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007
Y2 - 20 May 2007 through 24 May 2007
ER -