TY - JOUR
T1 - Synthetic green fluorescent protein chromophore analogues with a positive charge at the phenyl-like group
AU - Zhang, Zhao Yi
AU - Sung, Robert
AU - Sung, Kuangsen
N1 - Funding Information:
Acknowledgements We thank National Science Council of Taiwan for financial support (NSC104-2119-M-006-013), and H.-L. Fu for doing some work in this research.
Publisher Copyright:
© 2017, Springer-Verlag GmbH Austria.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Synthetic green fluorescent protein (GFP) chromophore analogues with a positive charge at the phenyl-like group have the highly electrophilic amidine carbon, smaller LUMO–HOMO energy gap, red-shifted electronic absorptions and fluorescent emissions, and accelerated E-Z thermoisomerization rates. They are water-labile and their hydrolysis results in ring-opening of the imidazolinone moiety with a half life around 25–37 h in D2O at 25 °C.
AB - Synthetic green fluorescent protein (GFP) chromophore analogues with a positive charge at the phenyl-like group have the highly electrophilic amidine carbon, smaller LUMO–HOMO energy gap, red-shifted electronic absorptions and fluorescent emissions, and accelerated E-Z thermoisomerization rates. They are water-labile and their hydrolysis results in ring-opening of the imidazolinone moiety with a half life around 25–37 h in D2O at 25 °C.
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U2 - 10.1007/s00726-017-2500-8
DO - 10.1007/s00726-017-2500-8
M3 - Article
C2 - 28988398
AN - SCOPUS:85030678808
SN - 0939-4451
VL - 50
SP - 141
EP - 147
JO - Amino Acids
JF - Amino Acids
IS - 1
ER -