Technetium-99m(V)-DMSA and gallium-67 in the assessment of bone and joint infection

Bi Fang Lee, Nan Tsing Chiu, Je Ken Chang, Gin Chung Liu, Hsin Su Yu

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34 Citations (Scopus)


The aim of our study was to investigate the diagnostic value of scans with 99mTc(V)-dimercaptosuccinic acid (DMSA) to localize bone and joint infection compared with scans using 67Ga. Methods: Thirty-six patients referred for investigation of bone and joint infection were studied. In all patients, a bone scan was obtained initially. Subsequently, comparative scans with 99mTc(V)-DMSA and 67Ga were performed 1 wk apart. Microbiological findings, pathologic findings and/or clinical follow-up (until symptoms disappeared) were considered to be proof of the presence of bone and joint infection. Results: Technetium-99m (V)-DMSA showed greater sensitivity and accuracy than 67Ga in the assessment of bone and joint infection, although the difference was not statistically significant. Conclusion: In comparison with a 67Ga scan, a 99mTc(V)-DMSA scan, in combination with a bone scan, is a reliable way to diagnose bone and joint infection. Both tracers were useful in the diagnosis of bone and joint infection.

Original languageEnglish
Pages (from-to)2128-2131
Number of pages4
JournalJournal of Nuclear Medicine
Issue number12
Publication statusPublished - 1998 Dec

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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