Temperaments × genes in bipolar I and bipolar II disorder patients

Ching I. Lin, Sheng Yu Lee, Yun Hsuan Chang, Jo Yung Wei Wu, Yi Syuan Wu, Pei Lin Wu, Hui Chun Chen, Shiou Lan Chen, I. Hui Lee, Tzung Lieh Yeh, Yen Kuang Yang, Huei Chen Ko, Ru Band Lu

Research output: Contribution to journalArticle

15 Citations (Scopus)


We found the main effects of harm avoidance temperament in predicting bipolar I and II, but the interaction between novelty seeking and Ser9Gly polymorphisms of dopamine D3 receptor gene was demonstrated in bipolar-I patients only. This study provided evidence that differences existed between BP-I and BPII in gene and temperament interactions.

Original languageEnglish
Pages (from-to)364-366
Number of pages3
JournalPsychiatry Research
Issue number3
Publication statusPublished - 2010 May 1

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Biological Psychiatry

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  • Cite this

    Lin, C. I., Lee, S. Y., Chang, Y. H., Wu, J. Y. W., Wu, Y. S., Wu, P. L., Chen, H. C., Chen, S. L., Lee, I. H., Yeh, T. L., Yang, Y. K., Ko, H. C., & Lu, R. B. (2010). Temperaments × genes in bipolar I and bipolar II disorder patients. Psychiatry Research, 177(3), 364-366. https://doi.org/10.1016/j.psychres.2010.03.005