TY - JOUR
T1 - Terahertz microchip for illicit drug detection
AU - Lu, Ja Yu
AU - Chen, Li Jin
AU - Kao, Tzeng Fu
AU - Chang, Hsu Hao
AU - Chen, Hung Wen
AU - Liu, An Shyi
AU - Chen, Yi Chun
AU - Wu, Ruey Beei
AU - Liu, Wei Sheng
AU - Chyi, Jeng Inn
AU - Sun, Chi Kuang
N1 - Funding Information:
Manuscript received March 6, 2006; revised July 2, 2006. This work was supported by the National Science Council of Taiwan under Grant NSC94-2215-E-002-007 and by the NTU Center for Genomic Medicine. J.-Y. Lu, L.-J. Chen, T.-F. Kao, H.-H. Chang, H.-W. Chen, and C.-K. Sun are with the Department of Electrical Engineering and Graduate Institute of ElectroOptical Engineering, National Taiwan University, Taipei 10617, Taiwan, R.O.C. (e-mail: [email protected]). A.-S. Liu, Y.-C. Chen, and R.-B. Wu are with the Department of Electrical Engineering, National Taiwan University, Taipei 10617, Taiwan, R.O.C. W.-S. Liu and J.-I. Chyi are with the Optical Sciences Center, National Central University, Chung-Li 32054, Taiwan, R.O.C. Digital Object Identifier 10.1109/LPT.2006.883285 Fig. 1. (a) THz-integrated biosensing chip which is composed of a PE sample cell with microchannels therein, a 150-m-thick glass substrate, and an integrated membrane-type THz photonic transmitter on the bottom of the glass substrate with a thickness of 5 m. (b) Bottom view of the device showing the electronic circuit of the photonic transmitter [9].
PY - 2006/11/1
Y1 - 2006/11/1
N2 - To accurately detect minute amounts of substances without disturbing the surroundings of target molecules has been a major goal in bioanalytical technology. Here by integrating an optoelectronic terahertz (THz) microsource into a glass-substrated microchip within the near-field distance, we demonstrate a compact, label-free, noninvasive, and sensitive microbiosensing system with low-power consumption. The demonstrated THz microchip allows us to locally specify various illicit drug powders with weights of nanograms, with a promising future for rapid identification of the static status or even the dynamics of various biomolecules.
AB - To accurately detect minute amounts of substances without disturbing the surroundings of target molecules has been a major goal in bioanalytical technology. Here by integrating an optoelectronic terahertz (THz) microsource into a glass-substrated microchip within the near-field distance, we demonstrate a compact, label-free, noninvasive, and sensitive microbiosensing system with low-power consumption. The demonstrated THz microchip allows us to locally specify various illicit drug powders with weights of nanograms, with a promising future for rapid identification of the static status or even the dynamics of various biomolecules.
UR - https://www.scopus.com/pages/publications/40549104920
UR - https://www.scopus.com/pages/publications/40549104920#tab=citedBy
U2 - 10.1109/LPT.2006.883285
DO - 10.1109/LPT.2006.883285
M3 - Article
AN - SCOPUS:40549104920
SN - 1041-1135
VL - 18
SP - 2254
EP - 2256
JO - IEEE Photonics Technology Letters
JF - IEEE Photonics Technology Letters
IS - 21
ER -