Terminating prolonged refractory status epilepticus using ketamine

Cheng Yang Hsieh, Pi-Shan Sung, Jing Jane Tsai, Chin-Wei Huang

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)


Refractory status epilepticus (RSE) is an emergent and difficult neurologic problem that is not uncommon in clinical practice. In this report, we describe a 23-year-old man whose RSE was refractory to standard antiepileptic drugs and barbiturates; it was successfully terminated only with intravenous ketamine. In this report, we evaluated and discuss the clinical and electroencephalographic effects under ketamine. This case and the rare cases of ketamine experience in RSE reported in the literature show that ketamine is potentially effective to use when treating patients with RSE. Further clinical trials are warranted, however.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalClinical Neuropharmacology
Issue number3
Publication statusPublished - 2010 May 1

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Pharmacology
  • Clinical Neurology

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