Terpenoids from the octocorals Menella sp. (plexauridae) and Lobophytum crassum (alcyonacea)

Cheng Hung Lee, Chia Ying Kao, Shih Yao Kao, Chih Han Chang, Jui Hsin Su, Tsong Long Hwang, Yueh Hsiung Kuo, Zhi Hong Wen, Ping Jyun Sung

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24 Citations (Scopus)

Abstract

A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound 2 was found to display a significant inhibitory effect on the release of elastase by human neutrophils.

Original languageEnglish
Pages (from-to)427-438
Number of pages12
JournalMarine Drugs
Volume10
Issue number2
DOIs
Publication statusPublished - 2012 Feb

All Science Journal Classification (ASJC) codes

  • Drug Discovery

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  • Cite this

    Lee, C. H., Kao, C. Y., Kao, S. Y., Chang, C. H., Su, J. H., Hwang, T. L., Kuo, Y. H., Wen, Z. H., & Sung, P. J. (2012). Terpenoids from the octocorals Menella sp. (plexauridae) and Lobophytum crassum (alcyonacea). Marine Drugs, 10(2), 427-438. https://doi.org/10.3390/md10020427