TY - JOUR
T1 - The alkaloids and other constituents from the root and stem of Aristolochia elegans
AU - Shi, Li Shian
AU - Kuo, Ping Chung
AU - Tsai, Yao Lung
AU - Damu, Amooru Gangaiah
AU - Wu, Tian Shung
N1 - Funding Information:
We thank the National Science Council, R.O.C. (NSC 86-2113-M-006-008) for support of this research.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2004/1/15
Y1 - 2004/1/15
N2 - Two new aristolactams, aristolactam E (1) and aristolactam-AIIIa-6-O- β-D-glucoside (2), three novel benzoyl benzyltetrahydroisoquinoline ether N-oxide alkaloids, aristoquinoline A (3), aristoquinoline B (4), and aristoquinoline C (5), and a new biphenyl ether, aristogin F (6), together with 62 known compounds have been isolated from the root and stem of Aristolochia elegans Mast. The structures of the new natural products were established on the basis of spectral evidence. Some of the isolated compounds were examined for their antioxidative and antityrosinase activities. Occurrence of the isoquinolones, biphenyl ethers, and benzoyl benzyltetrahydroisoquinoline ether alkaloids in the same plant indicated the definite possibility of these metabolites as biotransformation intermediates of bisbenzyltetrahydroisoquinoline alkaloids. This can be useful to solve the catabolic process of bisbenzyltetrahydroisoquinoline alkaloids.
AB - Two new aristolactams, aristolactam E (1) and aristolactam-AIIIa-6-O- β-D-glucoside (2), three novel benzoyl benzyltetrahydroisoquinoline ether N-oxide alkaloids, aristoquinoline A (3), aristoquinoline B (4), and aristoquinoline C (5), and a new biphenyl ether, aristogin F (6), together with 62 known compounds have been isolated from the root and stem of Aristolochia elegans Mast. The structures of the new natural products were established on the basis of spectral evidence. Some of the isolated compounds were examined for their antioxidative and antityrosinase activities. Occurrence of the isoquinolones, biphenyl ethers, and benzoyl benzyltetrahydroisoquinoline ether alkaloids in the same plant indicated the definite possibility of these metabolites as biotransformation intermediates of bisbenzyltetrahydroisoquinoline alkaloids. This can be useful to solve the catabolic process of bisbenzyltetrahydroisoquinoline alkaloids.
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U2 - 10.1016/j.bmc.2003.10.031
DO - 10.1016/j.bmc.2003.10.031
M3 - Article
C2 - 14723962
AN - SCOPUS:0347951161
SN - 0968-0896
VL - 12
SP - 439
EP - 446
JO - Bioorganic and Medicinal Chemistry
JF - Bioorganic and Medicinal Chemistry
IS - 2
ER -