The association between right ventricular free wall strain and exercise capacity for health check-up subjects

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Abstract

Background: Right ventricular (RV) function has been found to be a major factor of exercise capacity in patients with heart failure. However, the role of RV function in exercise capacity in healthy subjects has not been well studied. This study aims to validate the role of RV strain derived from speckle tracking echocardiography for exercise capacity for health check-up subjects. Methods: This study prospectively recruited subjects from a routine health examination. All of them were symptom free. RV function represented by RV strain was derived from speckle tracking echocardiography in addition to traditional echocardiography parameters. Functional capacity was determined by a symptom limited treadmill exercise test with the Bruce protocol. Results: Among 164 recruited subjects (age 52.2 ±9.2 years, 66.4% male), 32 subjects represented impaired functional capacity (MET<8), which was significantly correlated with age, left ventricular mass index, left ventricular filling pressure (E/e′), global longitudinal strain of the left ventricle (LVGLS) (-16.0±2.5% vs. -18.9±3.8%, p < 0.001) and RV free wall strain (RVLS-FW) (-17.0±4.9% vs. -21.9±3.2%, p <0.001). After multivariate logistic regression, RVS-FW was an independent predictor for impaired functional capacity (OR 1.62, CI1.32-1.98; p <0.001). Conclusions: In conclusion, RV strain is independently associated with exercise capacity for health check-up subjects. RV function is an important factor for functional capacity.

Original languageEnglish
Article numbere0173307
JournalPloS one
Volume12
Issue number3
DOIs
Publication statusPublished - 2017 Mar 1

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Right Ventricular Function
exercise
Echocardiography
Health
Exercise
echocardiography
Exercise Test
Speckle
signs and symptoms (animals and humans)
Ventricular Pressure
Exercise equipment
exercise test
Heart Ventricles
exercise equipment
heart failure
Healthy Volunteers
Heart Failure
Logistic Models
Logistics

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

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title = "The association between right ventricular free wall strain and exercise capacity for health check-up subjects",
abstract = "Background: Right ventricular (RV) function has been found to be a major factor of exercise capacity in patients with heart failure. However, the role of RV function in exercise capacity in healthy subjects has not been well studied. This study aims to validate the role of RV strain derived from speckle tracking echocardiography for exercise capacity for health check-up subjects. Methods: This study prospectively recruited subjects from a routine health examination. All of them were symptom free. RV function represented by RV strain was derived from speckle tracking echocardiography in addition to traditional echocardiography parameters. Functional capacity was determined by a symptom limited treadmill exercise test with the Bruce protocol. Results: Among 164 recruited subjects (age 52.2 ±9.2 years, 66.4{\%} male), 32 subjects represented impaired functional capacity (MET<8), which was significantly correlated with age, left ventricular mass index, left ventricular filling pressure (E/e′), global longitudinal strain of the left ventricle (LVGLS) (-16.0±2.5{\%} vs. -18.9±3.8{\%}, p < 0.001) and RV free wall strain (RVLS-FW) (-17.0±4.9{\%} vs. -21.9±3.2{\%}, p <0.001). After multivariate logistic regression, RVS-FW was an independent predictor for impaired functional capacity (OR 1.62, CI1.32-1.98; p <0.001). Conclusions: In conclusion, RV strain is independently associated with exercise capacity for health check-up subjects. RV function is an important factor for functional capacity.",
author = "Chang, {Wei Ting} and Yen-Wen Liu and Ping-Yen Liu and Chin-Hsin Hsu and Wei-Chuan Tsai",
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T1 - The association between right ventricular free wall strain and exercise capacity for health check-up subjects

AU - Chang, Wei Ting

AU - Liu, Yen-Wen

AU - Liu, Ping-Yen

AU - Hsu, Chin-Hsin

AU - Tsai, Wei-Chuan

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Background: Right ventricular (RV) function has been found to be a major factor of exercise capacity in patients with heart failure. However, the role of RV function in exercise capacity in healthy subjects has not been well studied. This study aims to validate the role of RV strain derived from speckle tracking echocardiography for exercise capacity for health check-up subjects. Methods: This study prospectively recruited subjects from a routine health examination. All of them were symptom free. RV function represented by RV strain was derived from speckle tracking echocardiography in addition to traditional echocardiography parameters. Functional capacity was determined by a symptom limited treadmill exercise test with the Bruce protocol. Results: Among 164 recruited subjects (age 52.2 ±9.2 years, 66.4% male), 32 subjects represented impaired functional capacity (MET<8), which was significantly correlated with age, left ventricular mass index, left ventricular filling pressure (E/e′), global longitudinal strain of the left ventricle (LVGLS) (-16.0±2.5% vs. -18.9±3.8%, p < 0.001) and RV free wall strain (RVLS-FW) (-17.0±4.9% vs. -21.9±3.2%, p <0.001). After multivariate logistic regression, RVS-FW was an independent predictor for impaired functional capacity (OR 1.62, CI1.32-1.98; p <0.001). Conclusions: In conclusion, RV strain is independently associated with exercise capacity for health check-up subjects. RV function is an important factor for functional capacity.

AB - Background: Right ventricular (RV) function has been found to be a major factor of exercise capacity in patients with heart failure. However, the role of RV function in exercise capacity in healthy subjects has not been well studied. This study aims to validate the role of RV strain derived from speckle tracking echocardiography for exercise capacity for health check-up subjects. Methods: This study prospectively recruited subjects from a routine health examination. All of them were symptom free. RV function represented by RV strain was derived from speckle tracking echocardiography in addition to traditional echocardiography parameters. Functional capacity was determined by a symptom limited treadmill exercise test with the Bruce protocol. Results: Among 164 recruited subjects (age 52.2 ±9.2 years, 66.4% male), 32 subjects represented impaired functional capacity (MET<8), which was significantly correlated with age, left ventricular mass index, left ventricular filling pressure (E/e′), global longitudinal strain of the left ventricle (LVGLS) (-16.0±2.5% vs. -18.9±3.8%, p < 0.001) and RV free wall strain (RVLS-FW) (-17.0±4.9% vs. -21.9±3.2%, p <0.001). After multivariate logistic regression, RVS-FW was an independent predictor for impaired functional capacity (OR 1.62, CI1.32-1.98; p <0.001). Conclusions: In conclusion, RV strain is independently associated with exercise capacity for health check-up subjects. RV function is an important factor for functional capacity.

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