The constituents of the root and stem of Aristolochia cucurbitifolia hayata and their biological activity

Tian Shung Wu, Yu Yi Chan, Yann Lii Leu

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Four new compounds, three phenanthrene derivatives, aristolochic acid-III methyl ester (1), cepharanone C (2), and sodium 7-hydroxyl-8-methoxyaristolate (3), and the benzoate derivative, sodium 3,4-dimethoxybenzoate (4), together with 53 known compounds were isolated and characterized from the fresh root and stem of Aristolochia cucurbitifolia. Their structures were elucidated by spectral analyses and chemical transformations. The cytotoxicity and antiplatelet activity of the isolated compounds are also discussed.

Original languageEnglish
Pages (from-to)1006-1009
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume48
Issue number7
DOIs
Publication statusPublished - 2000 Jul

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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