TY - JOUR
T1 - The correlation between waist-hip ratio and achieving therapeutic lipid goals in Taiwan
AU - Tsai, Hsing Shan
AU - Tseng, Wei Kung
AU - Yin, Wei Hsian
AU - Lin, Fang Ju
AU - Hsuan, Chen Feng
AU - Wu, Yen Wen
AU - Huang, Lien Chi
AU - Lin, Tsung Hsien
AU - Chang, Kuan Cheng
AU - Li, Yi Heng
AU - Yeh, Hung I.
AU - Chen, Jaw Wen
AU - Wu, Chau Chung
N1 - Funding Information:
Received: April 3, 2018 Accepted: April 3, 2019 1Division of Cardiology, Department of Internal Medicine, E-DA Hospital/I-Shou University; 2Department of Medical Imaging and Radiological Sciences, I-Shou University, Kaohsiung; 3National Yang-Ming University School of Medicine; 4Division of Cardiology, Heart Center, Cheng-Hsin General Hospital; 5Graduate Institute of Clinical Pharmacy, College of Medicine; 6School of Pharmacy, College of Medicine, National Taiwan University; 7Department of Pharmacy, National Taiwan University Hospital; 8Departments of Nuclear Medicine, and Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei; 9Cardiology Division of Cardiovascular Medical Center and Department of Nuclear Medicine, Far Eastern Memorial Hospital, New Taipei City; 10Division of Cardiology, Taipei City Hospital Heping Fuyou Branch, Taipei; 11Faculty of Medicine, Kaohsiung Medical University, Kaohsiung; 12Graduate Institute of Clinical Medical Science, China Medical University; 13Division of Cardiovascular Medicine; 14Cardiovascular Research Laboratory, China Medical University Hospital, Taichung; 15Department of Internal Medicine, National Cheng Kung University Hospital and College of Medicine, Tainan; 16Mackay Memorial Hospital, Mackay Medical College, New Taipei City; 17Department of Medical Research and Education, Taipei Veterans General Hospital; 18Institute of Pharmacology, National Yang-Ming University; 19Cardiology Division, Department of Internal Medicine, National Taiwan University Hospital; 20Graduate Institute of Medical Education & Bioethics, College of Medicine, National Taiwan University, Taipei, Taiwan. Corresponding author: Dr. Wei-Kung Tseng, Division of Cardiology, Department of Internal Medicine, E-Da Hospital, No. 1, Yi-Da Road, Jiau-Shu Village, Yan-Chau District, Kaohsiung 824, Taiwan. Tel: 886-7-615-0011 ext. 5005; Fax: 886-7-615-5352; E-mail: arthurtseng@me. com, [email protected]
Publisher Copyright:
© 2019, Republic of China Society of Cardiology. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Background: Body mass index (BMI), waist circumference (WC) and waist-hip ratio (WHR) are all simple anthropometric tools used to categorize obesity status. This study aimed to determine associations between different anthropometric indices and the attainment of therapeutic lipid goals in patients with atherosclerotic cardiovascular disease (CVD) undergoing secondary prevention. Methods: Between 2010 and 2014, this multi-center study enrolled 5718 patients undergoing secondary prevention for CVD. At study enrollment, total cholesterol, high-density lipoprotein protein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) were recorded. This cross-sectional study analyzed these three anthropometric obesity indices and correlations with achieving therapeutic lipid goals. Results: Among the 5718 patients, multivariate analysis revealed that those with higher BMI or WC tended not to meet their HDL-C and TG therapeutic goals. However, neither BMI nor WC showed a relationship with achieving the LDL-C target. The patients with an elevated WHR (± 0.98 for males and ± 0.97 for females) were less likely to achieve all three lipid target values, including LDL-C (p = 0.05), HDL-C (p < 0.001) and TG (p < 0.001). Conclusions: Among Taiwanese patients undergoing secondary prevention for CVD, the higher the WHR the lower the likelihood of achieving the lipid therapeutic goals.
AB - Background: Body mass index (BMI), waist circumference (WC) and waist-hip ratio (WHR) are all simple anthropometric tools used to categorize obesity status. This study aimed to determine associations between different anthropometric indices and the attainment of therapeutic lipid goals in patients with atherosclerotic cardiovascular disease (CVD) undergoing secondary prevention. Methods: Between 2010 and 2014, this multi-center study enrolled 5718 patients undergoing secondary prevention for CVD. At study enrollment, total cholesterol, high-density lipoprotein protein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) were recorded. This cross-sectional study analyzed these three anthropometric obesity indices and correlations with achieving therapeutic lipid goals. Results: Among the 5718 patients, multivariate analysis revealed that those with higher BMI or WC tended not to meet their HDL-C and TG therapeutic goals. However, neither BMI nor WC showed a relationship with achieving the LDL-C target. The patients with an elevated WHR (± 0.98 for males and ± 0.97 for females) were less likely to achieve all three lipid target values, including LDL-C (p = 0.05), HDL-C (p < 0.001) and TG (p < 0.001). Conclusions: Among Taiwanese patients undergoing secondary prevention for CVD, the higher the WHR the lower the likelihood of achieving the lipid therapeutic goals.
UR - http://www.scopus.com/inward/record.url?scp=85075069070&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85075069070&partnerID=8YFLogxK
U2 - 10.6515/ACS.201911_35(6).20190403A
DO - 10.6515/ACS.201911_35(6).20190403A
M3 - Article
AN - SCOPUS:85075069070
SN - 1011-6842
VL - 35
SP - 605
EP - 614
JO - Acta Cardiologica Sinica
JF - Acta Cardiologica Sinica
IS - 6
ER -