The design of a half-bridge series-resonant type heating system for magnetic nanoparticle thermotherapy

Cheng-Chi Tai, Chien Chang Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Application of magnetic materials for hyperthermia of biological tissue has been known, in principle, for more than four decades. Many empirical works were done in order to confirm a therapeutic effect on several types of tumors by performing experiments with animals or using cancerous cell cultures. The main idea of magnetic nanoparticle (MNP) thermotherapy is to utilize 7- to 50-nm diameter of ferric oxide (Fe3O4)particles which are heated up to 42°C under AC magnetic field for cancer therapy applications. In order to achieve the goal of killing cancer cells using the AC magnetic field, we designed a heating system to generate magnetic field which can be focused and frequency adjustable. This study adopts the half-bridge series-resonant type circuit as the core scheme of the heating system, and utilizes the frequency-adjustable design to conduct the heating experiment. The experiment results show that the designed coil and the heating system can warm up the magnetic nanoparticle 6°C in 32 minutes.

Original languageEnglish
Title of host publicationProgress in Electromagnetics Research Symposium 2008, PIERS 2008 Hangzhou
PublisherElectromagnetics Academy
Pages606-610
Number of pages5
Volume1
ISBN (Print)9781618390530
Publication statusPublished - 2008
EventProgress in Electromagnetics Research Symposium 2008, PIERS 2008 Hangzhou - Hangzhou, China
Duration: 2008 Mar 242008 Mar 28

Other

OtherProgress in Electromagnetics Research Symposium 2008, PIERS 2008 Hangzhou
CountryChina
CityHangzhou
Period08-03-2408-03-28

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

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