@inproceedings{7f89dc630a904cdbaaf6a2aec3fc847a,
title = "The development of multifunctional nanocomplexs for drug delivery in oral cancer therapy",
abstract = "Oral cancer has been denoted as the sixth most common cancer in the world. Chemotherapy is one of the major therapeutics for advanced oral cancer cases. Advances in drug delivery system draw a niche for cancer treatment due to improved local therapeutic concentration, side effect control and pharmacokinetic profile. A novel drug delivery system made of superparamagnetic iron oxide nanoparticles (SPIONs) covalently linked with alginate was developed for oral cancer therapy. The results suggest that Fe3O4@Ca-alginate nanoparticles could effectively release doxorubicin in a spatial-temporal controlled manner and even achieved higher release rate in cancer intracellular compartments. These data suggest that Fe3O4@Ca-alginate could be a potential candidate of advanced drug delivery systems for advanced cancer therapy.",
author = "Cheng, {F. Y.} and Tsai, {C. H.} and Shieh, {D. B.} and Huang, {J. S.}",
year = "2016",
month = jan,
day = "1",
language = "English",
series = "Advanced Materials - TechConnect Briefs 2016",
publisher = "TechConnect",
pages = "148--151",
editor = "Matthew Laudon and Fiona Case and Fiona Case and Bart Romanowicz and Bart Romanowicz",
booktitle = "Biotech, Biomaterials and Biomedical - TechConnect Briefs 2016",
note = "10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 19th Annual Nanotech Conference and Expo, and the 2016 National SBIR/STTR Conference ; Conference date: 22-05-2016 Through 25-05-2016",
}