The effects of Ginkgo biloba extracts on the memory and motor functions of rats with chronic cerebral insufficiency

Chou Ching K. Lin; Wen Ling Cheng; Shan Hui Hsu; Chieh Ming J. Chang

doi:10.1159/000068875

The effects of Ginkgo biloba extracts on the memory and motor functions of rats with chronic cerebral insufficiency

Chou Ching K. Lin, Wen Ling Cheng, Shan Hui Hsu, Chieh Ming J. Chang

Department of Neurology

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

The main goal of the curren study was to investigate the effects of two Ginkgo leaf extracts, EGb 761 and an extract of local Ginkgo leaf (LGb), on the memory and motor functions of rats with chronic cerebral insufficiency (produced by bilateral common carotid artery ligation). After the operation, spatial memory and motor functions were tested for over 80 days. Tests included (1) radial-arm maze test for testing spatial memory and locomotor activity and (2) muscle force and hind limbs for escape. The results indicate that both EGb 761 and LGb improved spatial memory from the second week after operation, but only EGb 761 delayed deterioration of motor functions from the fifth week after operation.

Original language	English
Pages (from-to)	47-51
Number of pages	5
Journal	Neuropsychobiology
Volume	47
Issue number	1
DOIs	https://doi.org/10.1159/000068875
Publication status	Published - 2003

All Science Journal Classification (ASJC) codes

Neuropsychology and Physiological Psychology
Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1159/000068875

Cite this

@article{a9165463321c4bc6918987f3e8bd17a4,

title = "The effects of Ginkgo biloba extracts on the memory and motor functions of rats with chronic cerebral insufficiency",

abstract = "The main goal of the curren study was to investigate the effects of two Ginkgo leaf extracts, EGb 761 and an extract of local Ginkgo leaf (LGb), on the memory and motor functions of rats with chronic cerebral insufficiency (produced by bilateral common carotid artery ligation). After the operation, spatial memory and motor functions were tested for over 80 days. Tests included (1) radial-arm maze test for testing spatial memory and locomotor activity and (2) muscle force and hind limbs for escape. The results indicate that both EGb 761 and LGb improved spatial memory from the second week after operation, but only EGb 761 delayed deterioration of motor functions from the fifth week after operation.",

author = "Lin, {Chou Ching K.} and Cheng, {Wen Ling} and Hsu, {Shan Hui} and Chang, {Chieh Ming J.}",

year = "2003",

doi = "10.1159/000068875",

language = "English",

volume = "47",

pages = "47--51",

journal = "Neuropsychobiology",

issn = "0302-282X",

publisher = "S. Karger AG",

number = "1",

}

TY - JOUR

T1 - The effects of Ginkgo biloba extracts on the memory and motor functions of rats with chronic cerebral insufficiency

AU - Lin, Chou Ching K.

AU - Cheng, Wen Ling

AU - Hsu, Shan Hui

AU - Chang, Chieh Ming J.

PY - 2003

Y1 - 2003

N2 - The main goal of the curren study was to investigate the effects of two Ginkgo leaf extracts, EGb 761 and an extract of local Ginkgo leaf (LGb), on the memory and motor functions of rats with chronic cerebral insufficiency (produced by bilateral common carotid artery ligation). After the operation, spatial memory and motor functions were tested for over 80 days. Tests included (1) radial-arm maze test for testing spatial memory and locomotor activity and (2) muscle force and hind limbs for escape. The results indicate that both EGb 761 and LGb improved spatial memory from the second week after operation, but only EGb 761 delayed deterioration of motor functions from the fifth week after operation.

AB - The main goal of the curren study was to investigate the effects of two Ginkgo leaf extracts, EGb 761 and an extract of local Ginkgo leaf (LGb), on the memory and motor functions of rats with chronic cerebral insufficiency (produced by bilateral common carotid artery ligation). After the operation, spatial memory and motor functions were tested for over 80 days. Tests included (1) radial-arm maze test for testing spatial memory and locomotor activity and (2) muscle force and hind limbs for escape. The results indicate that both EGb 761 and LGb improved spatial memory from the second week after operation, but only EGb 761 delayed deterioration of motor functions from the fifth week after operation.

UR - http://www.scopus.com/inward/record.url?scp=0037262541&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037262541&partnerID=8YFLogxK

U2 - 10.1159/000068875

DO - 10.1159/000068875

M3 - Article

C2 - 12606845

AN - SCOPUS:0037262541

SN - 0302-282X

VL - 47

SP - 47

EP - 51

JO - Neuropsychobiology

JF - Neuropsychobiology

IS - 1

ER -

The effects of Ginkgo biloba extracts on the memory and motor functions of rats with chronic cerebral insufficiency

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this