Objective: The purpose of this study was to evaluate the safety and efficacy of a hemostatic puncture closure device (Angio-Seal Vascular Closure Device) in patients undergoing diagnostic and therapeutic cardiac catheterizations. Methods: All consecutive patients (n = 102) who received a hemostatic puncture closure device from January 2007 to May 2007 in the National Cheng Kung University Hospital were enrolled in the study. Of these, 45 (44%) patients received therapeutic cardiac catheterizations. Multivariate logistic regression analyses were used to determine the predictors of vascular complications. Results: Of 102 patients, there were 68 (67%) males, and the mean age was 67 ± 11 years. All devices were deployed successfully, and device dysfunction occurred in only one patient (0.98%), in whom successful hemostasis was achieved later by manual and sandbag compression. There were 17 patients (16.7%) with small hematoma (≦ 6 cm in diameter) and three (2.9%) with large hematoma after the procedure. Compared with patients in the diagnostic group, patients in the therapeutic group had insignificantly higher complications of large hematoma (n = 3) (6.7% vs 0%, p = 0.08). However, no patients developed pseudoaneurysms, arteriovenous fistulae, and late bleeding in need of vascular repairs and blood transfusion until 7 to 14 days after discharge in both groups. Using multivariate logistic regression method, older age (≧ 75 years) was the only risk factor for developing large hematoma. Conclusion: Angio-Seal device offers a safe and effective hemostasis of the femoral artery in patients undergoing diagnostic and therapeutic cardiac catheterizations with acceptable morbidity rates.
|Number of pages||7|
|Journal||Acta Cardiologica Sinica|
|Publication status||Published - 2007 Dec 1|
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine