The efficacy assessment of thigh volume in predicting intrauterine fetal growth restriction by three-dimensional ultrasound

Chiung Hsin Chang, Chen Hsiang Yu, Huei Chen Ko, Chu Ling Chen, Fong Ming Chang

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Intrauterine growth restriction (IUGR) is an important issue in perinatology. To assess the efficacy of fetal thigh volume (ThVol) in predicting IUGR, we undertook a prospective cross-sectional study using quantitative 3-D ultrasound (US). During the study period, 30 fetuses with IUGR and 282 fetuses with non-IUGR were included for the ThVol assessment in utero by 3-D US. All the fetuses were singletons and had follow-up to the delivery to determine whether they were complicated with IUGR or not. Our results showed fetal ThVol assessed by 3-D US can differentiate fetuses with IUGR from fetuses with non-IUGR well. Using the 10th percentile as the screening threshold, the sensitivity of fetal ThVol in predicting IUGR was 86.6%, with specificity 91.1%, predictive value of positive test 51.0%, predictive value of negative test 98.5% and accuracy 90.7%. In conclusion, fetal ThVol assessed by quantitative 3-D US can be used to predict fetuses with IUGR antenatally. We believe fetal ThVol assessment by 3-D US would be a useful test in detecting fetuses with IUGR.

Original languageEnglish
Pages (from-to)883-887
Number of pages5
JournalUltrasound in Medicine and Biology
Volume31
Issue number7
DOIs
Publication statusPublished - 2005 Jul

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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