The exposure and toxicities of polychlorinated dibenzo-paradioxin-like chemicals

H. Y. Chang, C. C. Lee, C. H. Kuei, Y. L. Guo

Research output: Contribution to journalReview articlepeer-review


Due to the carcinogenicity and the considerable impact on our environment and ecosystems, polychlorinated dibenzo-para-dioxins (Dioxins) and their structurally similar compounds such as polychlorinated dibenzo-para-furans (Furans) and polychlorinated biphenyls (PCBs) have become concerns to public health. Among them, 2,3,7,8 tetra-dioxin has been called the 'poison of the century' because it is the strongest hepatocarcinogen. The sources, exposure levels in various environmental media and corresponding environmental fates, number of significant episodes, and toxicities of these compounds were extensively reviewed. We concluded that, residual PCBs, further efforts should focus on reducing the harmful effects. However, for dioxins and furans, the challenges are to improve the technology to decrease the production of these impurities within the manufacturing process, and to develop the biotechnology to decompose these persistent compounds.

Original languageEnglish
Pages (from-to)13-27
Number of pages15
JournalChinese Journal of Public Health
Issue number1
Publication statusPublished - 1999

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health


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