TY - JOUR
T1 - The feasibility of anterior 180° 99m Tc-sestamibi parathyroid SPECT/CT
AU - Cheng, Ju Ling
AU - Hsu, Chien Chin
AU - Wang, Pei Wen
AU - Sung, Kuo Chiang
AU - Chiu, Nan Tsing
AU - Chiu, Lan Yi
AU - Huang, Yung Cheng
N1 - Funding Information:
This study was funded by the research grant (#CMRPG8H0551) from the Chang Gung Memorial Hospital in Kaohsiung.
Publisher Copyright:
© 2021, The Japanese Society of Nuclear Medicine.
PY - 2021/2
Y1 - 2021/2
N2 - Objective: For 99mTc-sestamibi parathyroid single photon emission computed tomography/computed tomography (SPECT/CT), the traditional full-arc 360° acquisition technique has been suggested but not the theoretically low tissue-attenuated anterior 180° method. We aimed to compare the diagnostic performances and target-to-background ratios of anterior 180° and 360° SPECT/CT imaging. Methods: Ninety-nine patients who underwent 99mTc-sestamibi scintigraphy and received a surgical–pathological diagnosis of parathyroid adenoma or hyperplasia were enrolled. The SPECT/CT reconstructed images with anterior 180° and full-arc 360° data were interpreted by two physicians using a scoring scale, and the lesions were semi-quantified using target-to-background ratios for both image sets. Results: In total, 113 abnormal parathyroid lesions were identified on the SPECT/CT images. The agreements of interpretation between the two image sets and readers were very good (κ value: 0.83–1.00). The accuracies of summative interpretation for the anterior 180° and full-arc 360° SPECT/CT were 83.04% and 82.46%, respectively. The target-to-background ratios were significantly higher for the anterior 180° than the full-arc 360° images (P < 0.01). Conclusions: The anterior 180° SPECT/CT technique, a time-saving method, can provide satisfactory diagnostic performance and superior lesion contrast compared with the full-arc 360° SPECT/CT technique in 99mTc-sestamibi parathyroid imaging.
AB - Objective: For 99mTc-sestamibi parathyroid single photon emission computed tomography/computed tomography (SPECT/CT), the traditional full-arc 360° acquisition technique has been suggested but not the theoretically low tissue-attenuated anterior 180° method. We aimed to compare the diagnostic performances and target-to-background ratios of anterior 180° and 360° SPECT/CT imaging. Methods: Ninety-nine patients who underwent 99mTc-sestamibi scintigraphy and received a surgical–pathological diagnosis of parathyroid adenoma or hyperplasia were enrolled. The SPECT/CT reconstructed images with anterior 180° and full-arc 360° data were interpreted by two physicians using a scoring scale, and the lesions were semi-quantified using target-to-background ratios for both image sets. Results: In total, 113 abnormal parathyroid lesions were identified on the SPECT/CT images. The agreements of interpretation between the two image sets and readers were very good (κ value: 0.83–1.00). The accuracies of summative interpretation for the anterior 180° and full-arc 360° SPECT/CT were 83.04% and 82.46%, respectively. The target-to-background ratios were significantly higher for the anterior 180° than the full-arc 360° images (P < 0.01). Conclusions: The anterior 180° SPECT/CT technique, a time-saving method, can provide satisfactory diagnostic performance and superior lesion contrast compared with the full-arc 360° SPECT/CT technique in 99mTc-sestamibi parathyroid imaging.
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U2 - 10.1007/s12149-020-01553-9
DO - 10.1007/s12149-020-01553-9
M3 - Article
C2 - 33389667
AN - SCOPUS:85098583050
SN - 0914-7187
VL - 35
SP - 203
EP - 210
JO - Annals of Nuclear Medicine
JF - Annals of Nuclear Medicine
IS - 2
ER -