The first reductive cyclization by lithium aluminum hydride: Stereospecific reductive cyclization of 1-(methoxycarbonylmethyl)imidazolidin-4-ones

Fu Lin Chen; Kuang-Sen Sung

doi:10.1016/j.tetlet.2006.02.121

The first reductive cyclization by lithium aluminum hydride: Stereospecific reductive cyclization of 1-(methoxycarbonylmethyl)imidazolidin-4-ones

Fu Lin Chen, Kuang-Sen Sung

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The first LiAlH₄-driven reductive cyclization of the bifunctional 1-(methoxycarbonylmethyl)imidazolidin-4-ones, (-)-1a-c or (+)-1a-c, stereospecifically generated the corresponding 1,6-diaza-4-oxa-bicyclo[3.2.1] octanes, (-)-3a-c or (+)-3a-c, with a novel bicyclic system.

Original language	English
Pages (from-to)	2899-2903
Number of pages	5
Journal	Tetrahedron Letters
Volume	47
Issue number	17
DOIs	https://doi.org/10.1016/j.tetlet.2006.02.121
Publication status	Published - 2006 Apr 24

All Science Journal Classification (ASJC) codes

Biochemistry
Organic Chemistry
Drug Discovery

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abstract = "The first LiAlH4-driven reductive cyclization of the bifunctional 1-(methoxycarbonylmethyl)imidazolidin-4-ones, (-)-1a-c or (+)-1a-c, stereospecifically generated the corresponding 1,6-diaza-4-oxa-bicyclo[3.2.1] octanes, (-)-3a-c or (+)-3a-c, with a novel bicyclic system.",

author = "Chen, {Fu Lin} and Kuang-Sen Sung",

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AU - Sung, Kuang-Sen

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AB - The first LiAlH4-driven reductive cyclization of the bifunctional 1-(methoxycarbonylmethyl)imidazolidin-4-ones, (-)-1a-c or (+)-1a-c, stereospecifically generated the corresponding 1,6-diaza-4-oxa-bicyclo[3.2.1] octanes, (-)-3a-c or (+)-3a-c, with a novel bicyclic system.

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