The first reductive cyclization by lithium aluminum hydride: Stereospecific reductive cyclization of 1-(methoxycarbonylmethyl)imidazolidin-4-ones

Fu Lin Chen, Kuang-Sen Sung

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The first LiAlH4-driven reductive cyclization of the bifunctional 1-(methoxycarbonylmethyl)imidazolidin-4-ones, (-)-1a-c or (+)-1a-c, stereospecifically generated the corresponding 1,6-diaza-4-oxa-bicyclo[3.2.1] octanes, (-)-3a-c or (+)-3a-c, with a novel bicyclic system.

Original languageEnglish
Pages (from-to)2899-2903
Number of pages5
JournalTetrahedron Letters
Volume47
Issue number17
DOIs
Publication statusPublished - 2006 Apr 24

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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