The recognition of platelets adhered images

Kuo-Sheng Cheng, J. S. Shyu, D. C. Chan, Jack Jen Chrauying Jack Jen

Research output: Contribution to journalArticle

Abstract

An in vitro flow system is usually used to investigate the distribution features of adhered platelets under different flow conditions. The four controlled conditions are: (1) fibrin-coated surface, shear rate 445/s; (2) fibrin-coated surface, shear rate 70/s; (3) fibrinogen-coated surface, shear rate 445/s; (4) fibrinogen-coated surface, shear rate 70/s. The purpose of this study is to apply image processing technique for quantitative analysis of the platelets images. The identification of platelets is realized by sequential procedures, including automatic thresholding, unit-platelet models computation and recognition of platelets' centers by comparing correlation coefficients. Based upon the measures of the number of identified platelets and the mass center of those platelets distribution, the accuracy of the platelets identification is more than 92% in average and is also better than the previous method. A simple GUI(Graphic User Interface) is also added for rendering the physiologists a user friendly man-machine interface.

Original languageEnglish
Pages (from-to)35-44
Number of pages10
JournalChinese Journal of Medical and Biological Engineering
Volume17
Issue number1
Publication statusPublished - 1997

Fingerprint

Platelets
Blood Platelets
Shear deformation
Fibrin
Fibrinogen
Platelet Count
User interfaces
Image processing
Chemical analysis

All Science Journal Classification (ASJC) codes

  • Biophysics

Cite this

Cheng, K-S., Shyu, J. S., Chan, D. C., & Chrauying Jack Jen, J. J. (1997). The recognition of platelets adhered images. Chinese Journal of Medical and Biological Engineering, 17(1), 35-44.
Cheng, Kuo-Sheng ; Shyu, J. S. ; Chan, D. C. ; Chrauying Jack Jen, Jack Jen. / The recognition of platelets adhered images. In: Chinese Journal of Medical and Biological Engineering. 1997 ; Vol. 17, No. 1. pp. 35-44.
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Cheng, K-S, Shyu, JS, Chan, DC & Chrauying Jack Jen, JJ 1997, 'The recognition of platelets adhered images', Chinese Journal of Medical and Biological Engineering, vol. 17, no. 1, pp. 35-44.

The recognition of platelets adhered images. / Cheng, Kuo-Sheng; Shyu, J. S.; Chan, D. C.; Chrauying Jack Jen, Jack Jen.

In: Chinese Journal of Medical and Biological Engineering, Vol. 17, No. 1, 1997, p. 35-44.

Research output: Contribution to journalArticle

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AU - Cheng, Kuo-Sheng

AU - Shyu, J. S.

AU - Chan, D. C.

AU - Chrauying Jack Jen, Jack Jen

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AB - An in vitro flow system is usually used to investigate the distribution features of adhered platelets under different flow conditions. The four controlled conditions are: (1) fibrin-coated surface, shear rate 445/s; (2) fibrin-coated surface, shear rate 70/s; (3) fibrinogen-coated surface, shear rate 445/s; (4) fibrinogen-coated surface, shear rate 70/s. The purpose of this study is to apply image processing technique for quantitative analysis of the platelets images. The identification of platelets is realized by sequential procedures, including automatic thresholding, unit-platelet models computation and recognition of platelets' centers by comparing correlation coefficients. Based upon the measures of the number of identified platelets and the mass center of those platelets distribution, the accuracy of the platelets identification is more than 92% in average and is also better than the previous method. A simple GUI(Graphic User Interface) is also added for rendering the physiologists a user friendly man-machine interface.

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