The relationships between daily life events and the availabilities of serotonin transporters and dopamine transporters in healthy volunteers-A dual-isotope SPECT study

Tzung Lieh Yeh; I. Hui Lee; Kao Ching Chen; Po See Chen; Wei Jen Yao; Yeng Kuang Yang; Nan Tsing Chiu; Ru Band Lu

doi:10.1016/j.neuroimage.2008.12.004

The relationships between daily life events and the availabilities of serotonin transporters and dopamine transporters in healthy volunteers-A dual-isotope SPECT study

Tzung Lieh Yeh, I. Hui Lee, Kao Ching Chen, Po See Chen, Wei Jen Yao, Yeng Kuang Yang, Nan Tsing Chiu, Ru Band Lu

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The aim of this study was to examine the relationships between the daily life events and the availabilities of serotonin transporters (SERT) and dopamine transporters (DAT) in healthy volunteers. Thirty-seven volunteers, 19 males and 18 females, were recruited. The SERT availability was approximated using SPECT and [¹²³I] ADAM while the DAT availability was approximated using SPECT and [^99mTc] TRODAT-1. All participants completed the Recent Life Change Questionnaire. The results showed that SERT and DAT may be sensitive to the presence of stressful events.

Original language	English
Pages (from-to)	275-279
Number of pages	5
Journal	NeuroImage
Volume	45
Issue number	2
DOIs	https://doi.org/10.1016/j.neuroimage.2008.12.004
Publication status	Published - 2009 Apr 1

All Science Journal Classification (ASJC) codes

Neurology
Cognitive Neuroscience

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10.1016/j.neuroimage.2008.12.004

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title = "The relationships between daily life events and the availabilities of serotonin transporters and dopamine transporters in healthy volunteers-A dual-isotope SPECT study",

abstract = "The aim of this study was to examine the relationships between the daily life events and the availabilities of serotonin transporters (SERT) and dopamine transporters (DAT) in healthy volunteers. Thirty-seven volunteers, 19 males and 18 females, were recruited. The SERT availability was approximated using SPECT and [123I] ADAM while the DAT availability was approximated using SPECT and [99mTc] TRODAT-1. All participants completed the Recent Life Change Questionnaire. The results showed that SERT and DAT may be sensitive to the presence of stressful events.",

author = "Yeh, {Tzung Lieh} and Lee, {I. Hui} and Chen, {Kao Ching} and Chen, {Po See} and Yao, {Wei Jen} and Yang, {Yeng Kuang} and Chiu, {Nan Tsing} and Lu, {Ru Band}",

note = "Funding Information: The authors gratefully acknowledge the financial support from the National Science Council of Taiwan (NSC-93-2314-B-006-107- and NSC-95-2314-B-006-115-MY2) and the administrative support of Mlles, Ching Lin Chu, Tsai Hua Chang, Yun-Hsuan Chang, Yi Wen Chen and Linda J. Chang.",

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T1 - The relationships between daily life events and the availabilities of serotonin transporters and dopamine transporters in healthy volunteers-A dual-isotope SPECT study

AU - Yeh, Tzung Lieh

AU - Lee, I. Hui

AU - Chen, Kao Ching

AU - Chen, Po See

AU - Yao, Wei Jen

AU - Yang, Yeng Kuang

AU - Chiu, Nan Tsing

AU - Lu, Ru Band

N1 - Funding Information: The authors gratefully acknowledge the financial support from the National Science Council of Taiwan (NSC-93-2314-B-006-107- and NSC-95-2314-B-006-115-MY2) and the administrative support of Mlles, Ching Lin Chu, Tsai Hua Chang, Yun-Hsuan Chang, Yi Wen Chen and Linda J. Chang.

PY - 2009/4/1

Y1 - 2009/4/1

N2 - The aim of this study was to examine the relationships between the daily life events and the availabilities of serotonin transporters (SERT) and dopamine transporters (DAT) in healthy volunteers. Thirty-seven volunteers, 19 males and 18 females, were recruited. The SERT availability was approximated using SPECT and [123I] ADAM while the DAT availability was approximated using SPECT and [99mTc] TRODAT-1. All participants completed the Recent Life Change Questionnaire. The results showed that SERT and DAT may be sensitive to the presence of stressful events.

AB - The aim of this study was to examine the relationships between the daily life events and the availabilities of serotonin transporters (SERT) and dopamine transporters (DAT) in healthy volunteers. Thirty-seven volunteers, 19 males and 18 females, were recruited. The SERT availability was approximated using SPECT and [123I] ADAM while the DAT availability was approximated using SPECT and [99mTc] TRODAT-1. All participants completed the Recent Life Change Questionnaire. The results showed that SERT and DAT may be sensitive to the presence of stressful events.

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The relationships between daily life events and the availabilities of serotonin transporters and dopamine transporters in healthy volunteers-A dual-isotope SPECT study

Abstract

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