The role of environmental allergen control in the management of asthma

Omer Kalayci, Michael Miligkos, César Fireth Pozo Beltrán, Zeinab A. El-Sayed, René Maximiliano Gómez, Elham Hossny, Peter Le Souef, Antonio Nieto, Wanda Phipatanakul, Paulo Marcio Pitrez, Paraskevi Xepapadaki, Wang Jiu-Yao, Nikolaos G. Papadopoulos

Research output: Contribution to journalReview articlepeer-review

18 Citations (Scopus)


Allergen exposure may exacerbate asthma symptoms in sensitized patients. Allergen reduction or avoidance measures have been widely utilized; however, there is ongoing controversy on the effectiveness of specific allergen control measures in the management of children with asthma. Often, allergen avoidance strategies are not recommended by guidelines because they can be complex or burdensome, although individual patients may benefit. Here we explore the potential for intervention against exposure to the major allergens implicated in asthma (ie, house dust mites, indoor molds, rodents, cockroaches, furry pets, and outdoor molds and pollens), and subsequent effects on asthma symptoms. We critically assess the available evidence regarding the clinical benefits of specific environmental control measures for each allergen. Finally, we underscore the need for standardized and multifaceted approaches in research and real-life settings, which would result in the identification of more personalized and beneficial prevention strategies.

Original languageEnglish
Article number100634
JournalWorld Allergy Organization Journal
Issue number3
Publication statusPublished - 2022 Mar

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine


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