Three-dimensional bone structure and bone mineral density evaluations of autogenous bone graft after sinus augmentation

A microcomputed tomography analysis

Heng Li Huang, Michael Yc Chen, Jui Ting Hsu, Yu Fen Li, Chih-Han Chang, Kuan Ting Chen

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective: The purpose of this study was to determine the relationships and differences in three-dimensional (3D) bone mineral density (BMD) and microtrabecular structures between autogenous bone grafts and their adjacent native bone after a healing period following maxillary sinus augmentation. Materials and methods: Nine rod-shaped human bone biopsy samples were taken from patients receiving two-stage sinus augmentation therapy in implantation areas and analyzed using microcomputed tomography (micro-CT). Before micro-CT scanning, two BMD phantoms were placed near to the bone biopsy samples for executing BMD calculations of the grafted and native bone samples. In addition, 3D structural parameters of the trabeculae were analyzed for both the grafted and native bone, including percentage of bone volume [bone volume (BV)/tissue volume (TV)], bone-specific surface [bone surface (BS)/BV], trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular separation (Tb.Sp), trabecular pattern factor (Tb.Pf), and structure model index (SMI). Results: No significant correlations with regard to BMD and trabecular-structure parameters were found between native bone and grafted bone; however, BS/BV and Tb.Pf were higher and Tb.Th and Tb.Sp were 37.35% and 12.74% lower in grafted bone than in native bone. For grafted bone, there were significant correlations (P < 0.05) between BMD and BV/TV, and Tb.N. Conclusions: When using autogenous bone as a graft material, BMD and micromorphological conditions of grafted bone were not influenced by the condition of the native bone in the maxilla. Differences were found in surface complexity, trabecular thickness, trabecular separation, and the connectivity of trabeculae between grafted and native bone. The BMD in grafted bone was affected by the quantity of the trabeculae.

Original languageEnglish
Pages (from-to)1098-1103
Number of pages6
JournalClinical Oral Implants Research
Volume23
Issue number9
DOIs
Publication statusPublished - 2012 Sep 1

Fingerprint

X-Ray Microtomography
Bone Density
Transplants
Bone and Bones
Sinus Floor Augmentation

All Science Journal Classification (ASJC) codes

  • Oral Surgery

Cite this

@article{06ccd5cb3cf64db1acaa7ce39b2d0c82,
title = "Three-dimensional bone structure and bone mineral density evaluations of autogenous bone graft after sinus augmentation: A microcomputed tomography analysis",
abstract = "Objective: The purpose of this study was to determine the relationships and differences in three-dimensional (3D) bone mineral density (BMD) and microtrabecular structures between autogenous bone grafts and their adjacent native bone after a healing period following maxillary sinus augmentation. Materials and methods: Nine rod-shaped human bone biopsy samples were taken from patients receiving two-stage sinus augmentation therapy in implantation areas and analyzed using microcomputed tomography (micro-CT). Before micro-CT scanning, two BMD phantoms were placed near to the bone biopsy samples for executing BMD calculations of the grafted and native bone samples. In addition, 3D structural parameters of the trabeculae were analyzed for both the grafted and native bone, including percentage of bone volume [bone volume (BV)/tissue volume (TV)], bone-specific surface [bone surface (BS)/BV], trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular separation (Tb.Sp), trabecular pattern factor (Tb.Pf), and structure model index (SMI). Results: No significant correlations with regard to BMD and trabecular-structure parameters were found between native bone and grafted bone; however, BS/BV and Tb.Pf were higher and Tb.Th and Tb.Sp were 37.35{\%} and 12.74{\%} lower in grafted bone than in native bone. For grafted bone, there were significant correlations (P < 0.05) between BMD and BV/TV, and Tb.N. Conclusions: When using autogenous bone as a graft material, BMD and micromorphological conditions of grafted bone were not influenced by the condition of the native bone in the maxilla. Differences were found in surface complexity, trabecular thickness, trabecular separation, and the connectivity of trabeculae between grafted and native bone. The BMD in grafted bone was affected by the quantity of the trabeculae.",
author = "Huang, {Heng Li} and Chen, {Michael Yc} and Hsu, {Jui Ting} and Li, {Yu Fen} and Chih-Han Chang and Chen, {Kuan Ting}",
year = "2012",
month = "9",
day = "1",
doi = "10.1111/j.1600-0501.2011.02273.x",
language = "English",
volume = "23",
pages = "1098--1103",
journal = "Clinical Oral Implants Research",
issn = "0905-7161",
publisher = "Blackwell Munksgaard",
number = "9",

}

Three-dimensional bone structure and bone mineral density evaluations of autogenous bone graft after sinus augmentation : A microcomputed tomography analysis. / Huang, Heng Li; Chen, Michael Yc; Hsu, Jui Ting; Li, Yu Fen; Chang, Chih-Han; Chen, Kuan Ting.

In: Clinical Oral Implants Research, Vol. 23, No. 9, 01.09.2012, p. 1098-1103.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Three-dimensional bone structure and bone mineral density evaluations of autogenous bone graft after sinus augmentation

T2 - A microcomputed tomography analysis

AU - Huang, Heng Li

AU - Chen, Michael Yc

AU - Hsu, Jui Ting

AU - Li, Yu Fen

AU - Chang, Chih-Han

AU - Chen, Kuan Ting

PY - 2012/9/1

Y1 - 2012/9/1

N2 - Objective: The purpose of this study was to determine the relationships and differences in three-dimensional (3D) bone mineral density (BMD) and microtrabecular structures between autogenous bone grafts and their adjacent native bone after a healing period following maxillary sinus augmentation. Materials and methods: Nine rod-shaped human bone biopsy samples were taken from patients receiving two-stage sinus augmentation therapy in implantation areas and analyzed using microcomputed tomography (micro-CT). Before micro-CT scanning, two BMD phantoms were placed near to the bone biopsy samples for executing BMD calculations of the grafted and native bone samples. In addition, 3D structural parameters of the trabeculae were analyzed for both the grafted and native bone, including percentage of bone volume [bone volume (BV)/tissue volume (TV)], bone-specific surface [bone surface (BS)/BV], trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular separation (Tb.Sp), trabecular pattern factor (Tb.Pf), and structure model index (SMI). Results: No significant correlations with regard to BMD and trabecular-structure parameters were found between native bone and grafted bone; however, BS/BV and Tb.Pf were higher and Tb.Th and Tb.Sp were 37.35% and 12.74% lower in grafted bone than in native bone. For grafted bone, there were significant correlations (P < 0.05) between BMD and BV/TV, and Tb.N. Conclusions: When using autogenous bone as a graft material, BMD and micromorphological conditions of grafted bone were not influenced by the condition of the native bone in the maxilla. Differences were found in surface complexity, trabecular thickness, trabecular separation, and the connectivity of trabeculae between grafted and native bone. The BMD in grafted bone was affected by the quantity of the trabeculae.

AB - Objective: The purpose of this study was to determine the relationships and differences in three-dimensional (3D) bone mineral density (BMD) and microtrabecular structures between autogenous bone grafts and their adjacent native bone after a healing period following maxillary sinus augmentation. Materials and methods: Nine rod-shaped human bone biopsy samples were taken from patients receiving two-stage sinus augmentation therapy in implantation areas and analyzed using microcomputed tomography (micro-CT). Before micro-CT scanning, two BMD phantoms were placed near to the bone biopsy samples for executing BMD calculations of the grafted and native bone samples. In addition, 3D structural parameters of the trabeculae were analyzed for both the grafted and native bone, including percentage of bone volume [bone volume (BV)/tissue volume (TV)], bone-specific surface [bone surface (BS)/BV], trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular separation (Tb.Sp), trabecular pattern factor (Tb.Pf), and structure model index (SMI). Results: No significant correlations with regard to BMD and trabecular-structure parameters were found between native bone and grafted bone; however, BS/BV and Tb.Pf were higher and Tb.Th and Tb.Sp were 37.35% and 12.74% lower in grafted bone than in native bone. For grafted bone, there were significant correlations (P < 0.05) between BMD and BV/TV, and Tb.N. Conclusions: When using autogenous bone as a graft material, BMD and micromorphological conditions of grafted bone were not influenced by the condition of the native bone in the maxilla. Differences were found in surface complexity, trabecular thickness, trabecular separation, and the connectivity of trabeculae between grafted and native bone. The BMD in grafted bone was affected by the quantity of the trabeculae.

UR - http://www.scopus.com/inward/record.url?scp=84865284195&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84865284195&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0501.2011.02273.x

DO - 10.1111/j.1600-0501.2011.02273.x

M3 - Article

VL - 23

SP - 1098

EP - 1103

JO - Clinical Oral Implants Research

JF - Clinical Oral Implants Research

SN - 0905-7161

IS - 9

ER -