TiCl 4-catalyzed synthesis of peroxyacetals from aldehydes

Chen Yu Tsai, Lu An Chen, Kuangsen Sung

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Peroxyacetals 2a-2j were prepared by TiCl 4-promoted nucleophilic addition of both tert-butyl hydroperoxide (TBHP) and an alcohol to the corresponding aldehyde. The reaction works well with a variety of aldehydes, but not with ketones. The magnitude of the equilibrium constant for hemiacetal formation plays an important role; a large constant enables high conversion to peroxyacetal.

Original languageEnglish
Pages (from-to)321-325
Number of pages5
JournalCanadian Journal of Chemistry
Issue number4
Publication statusPublished - 2012 Apr

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry
  • Organic Chemistry


Dive into the research topics of 'TiCl 4-catalyzed synthesis of peroxyacetals from aldehydes'. Together they form a unique fingerprint.

Cite this