TiCl 4-catalyzed synthesis of peroxyacetals from aldehydes

Chen Yu Tsai, Lu An Chen, Kuangsen Sung

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Peroxyacetals 2a-2j were prepared by TiCl 4-promoted nucleophilic addition of both tert-butyl hydroperoxide (TBHP) and an alcohol to the corresponding aldehyde. The reaction works well with a variety of aldehydes, but not with ketones. The magnitude of the equilibrium constant for hemiacetal formation plays an important role; a large constant enables high conversion to peroxyacetal.

Original languageEnglish
Pages (from-to)321-325
Number of pages5
JournalCanadian Journal of Chemistry
Volume90
Issue number4
DOIs
Publication statusPublished - 2012 Apr 1

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Organic Chemistry

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