Tolerized Microglia Protect Neurons Against Endotoxin-Induced TNF-α Production via an LBP-Dependent Intracellular p38 MAPK Signaling Pathway

Keyphrases

• Anti-tumor Necrosis Factor Antibody 8%
• Astroglia 8%
• C-Jun N-terminal Kinase 8%
• Chemical Inhibitors 8%
• Endotoxin 100%
• Endotoxin Tolerance 58%
• Enzyme-linked Immunosorbent Assay (ELISA) 8%
• Extracellular Signal-regulated Kinase 8%
• Immune Response 8%
• Inflammatory Cytokines 8%
• Interleukin-1β 8%
• Intracellular Signaling 8%
• Intrinsic Mechanism 8%
• Lipopolysaccharide 25%
• Lipopolysaccharide Challenge 8%
• Lipopolysaccharide-binding Protein 8%
• Lipopolysaccharide-induced 8%
• LPS-binding Protein 100%
• Microglia 100%
• Mitogen-activated Protein Kinase 8%
• Neuron-glia 8%
• Neuronal Damage 8%
• Neuroprotection 16%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 100%
• Pre-incubation 8%
• Prostaglandin E2 8%
• SB203580 8%
• Serum Binding 8%
• Tumor Necrosis Factor-α 100%

Neuroscience

• Amino Terminal Sequence 11%
• Astrocyte 11%
• Cell Signaling 100%
• extracellular signal regulated kinase 11%
• Glia 11%
• Interleukin 1beta 11%
• Intracellular Signaling 11%
• Kinase 11%
• Lipopolysaccharide 55%
• Lipopolysaccharide Binding Protein 100%
• Microglia 100%
• Neuroprotection 22%
• P38 Mitogen-Activated Protein Kinases 100%
• Proinflammatory Cytokine 11%
• Prostaglandin E2 11%
• Tumor Necrosis Factor Alpha 100%
• Tumor Necrosis Factor Antibody 11%

Medicine and Dentistry

• Lipopolysaccharide Binding Protein 100%