Toward personalization of asthma treatment according to trigger factors

Katarzyna Niespodziana, Kristina Borochova, Petra Pazderova, Thomas Schlederer, Natalia Astafyeva, Tatiana Baranovskaya, Mohamed Ridha Barbouche, Evgeny Beltyukov, Angelika Berger, Elena Borzova, Jean Bousquet, Roxana S. Bumbacea, Snezhana Bychkovskaya, Luis Caraballo, Kian Fan Chung, Adnan Custovic, Guillermo Docena, Thomas Eiwegger, Irina Evsegneeva, Alexander EmelyanovPeter Errhalt, Rustem Fassakhov, Rezeda Fayzullina, Elena Fedenko, Daria Fomina, Zhongshan Gao, Pedro Giavina-Bianchi, Maia Gotua, Susanne Greber-Platzer, Gunilla Hedlin, Natalia Ilina, Zhanat Ispayeva, Marco Idzko, Sebastian L. Johnston, Ömer Kalayci, Alexander Karaulov, Antonina Karsonova, Musa Khaitov, Elena Kovzel, Marek L. Kowalski, Dmitry Kudlay, Michael Levin, Svetlana Makarova, Paolo Maria Matricardi, Kari C. Nadeau, Leyla Namazova-Baranova, Olga Naumova, Oleksandr Nazarenko, Paul M. O'Byrne, Faith Osier, Alexander N. Pampura, Carmen Panaitescu, Nikolaos G. Papadopoulos, Hae Sim Park, Ruby Pawankar, Wolfgang Pohl, Harald Renz, Ksenja Riabova, Vanitha Sampath, Bülent E. Sekerel, Elopy Sibanda, Valérie Siroux, Ludmila P. Sizyakina, Jin Lyu Sun, Zsolt Szepfalusi, Tetiana Umanets, Hugo P.S. Van Bever, Marianne van Hage, Margarita Vasileva, Erika von Mutius, Jiu Yao Wang, Gary W.K. Wong, Sergii Zaikov, Mihaela Zidarn, Rudolf Valenta

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma.

Original languageEnglish
Pages (from-to)1529-1534
Number of pages6
JournalJournal of Allergy and Clinical Immunology
Volume145
Issue number6
DOIs
Publication statusPublished - 2020 Jun

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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  • Cite this

    Niespodziana, K., Borochova, K., Pazderova, P., Schlederer, T., Astafyeva, N., Baranovskaya, T., Barbouche, M. R., Beltyukov, E., Berger, A., Borzova, E., Bousquet, J., Bumbacea, R. S., Bychkovskaya, S., Caraballo, L., Chung, K. F., Custovic, A., Docena, G., Eiwegger, T., Evsegneeva, I., ... Valenta, R. (2020). Toward personalization of asthma treatment according to trigger factors. Journal of Allergy and Clinical Immunology, 145(6), 1529-1534. https://doi.org/10.1016/j.jaci.2020.02.001