Transverse elasticity and blood perfusion of sciatic nerves under in situ circular compression

Ming Shaung Ju, Chou Ching K. Lin, Jia Lin Fan, Rung Jian Chen

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Biomechanical properties and microcirculation of peripheral nerves under circular compression are vital factors for nerve repair and for developing neural prostheses. Quasi-static circular compression experiments on six rabbit sciatic nerves were performed. The mean estimated Young's modulus of the sciatic nerves in the transverse direction was 66.9±8.0 kPa. The blood perfusion of the nerve started to decrease at a mean pressure of 30.5 mmHg and reached a stable lower level of 30% of pre-compression value at 102.8 mmHg. The findings may make a contribution to safer design of cuff electrodes to be used in neural prostheses.

Original languageEnglish
Pages (from-to)97-102
Number of pages6
JournalJournal of Biomechanics
Volume39
Issue number1
DOIs
Publication statusPublished - 2006 Jan 1

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

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