TY - JOUR
T1 - Treadmill testing improves survival prediction models in pulmonary arterial hypertension
AU - Hsu, Chih Hsin
AU - Glassner, Cherylanne
AU - Foreman, Aimee J.
AU - Agarwal, Richa
AU - Benza, Raymond J.
AU - Frantz, Robert P.
AU - Gomberg-Maitland, Mardi
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2011/12
Y1 - 2011/12
N2 - Background: Six-minute walk distance (6MWD) is used in the REVEAL equation to predict 1-year survival for patients with pulmonary arterial hypertension. We sought to determine whether exercise treadmill testing (ETT) could be used in its place. Methods: This was a single-center study in which 449 patients were enrolled. The variables predictive of survival in the REVEAL equation were evaluated and compared with survival predicted by the REVEAL equation without an exercise measure and a revised equation using ETT. Results: The addition of ETT to the equation improved the predictive ability of the REVEAL equation in the high- and low-risk patient groups. Conclusion: The study findings suggest that the addition of ETT parameters to the REVEAL prognostic equation improves the predictive value of the equation when 6-minute walk distance is unavailable.
AB - Background: Six-minute walk distance (6MWD) is used in the REVEAL equation to predict 1-year survival for patients with pulmonary arterial hypertension. We sought to determine whether exercise treadmill testing (ETT) could be used in its place. Methods: This was a single-center study in which 449 patients were enrolled. The variables predictive of survival in the REVEAL equation were evaluated and compared with survival predicted by the REVEAL equation without an exercise measure and a revised equation using ETT. Results: The addition of ETT to the equation improved the predictive ability of the REVEAL equation in the high- and low-risk patient groups. Conclusion: The study findings suggest that the addition of ETT parameters to the REVEAL prognostic equation improves the predictive value of the equation when 6-minute walk distance is unavailable.
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U2 - 10.1016/j.ahj.2011.09.015
DO - 10.1016/j.ahj.2011.09.015
M3 - Article
C2 - 22137074
AN - SCOPUS:82555187068
VL - 162
SP - 1011
EP - 1017
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 6
ER -