Trinorditerpenes from the roots of Flueggea virosa

Chih Hua Chao; Ju Chien Cheng; Tsong Long Hwang; De Yang Shen; Tian Shung Wu

doi:10.1016/j.bmcl.2013.12.051

Trinorditerpenes from the roots of Flueggea virosa

Chih Hua Chao, Ju Chien Cheng, Tsong Long Hwang, De Yang Shen, Tian Shung Wu

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Two trinorditerpenes, flueggrenes A and B (1 and 2), have been isolated from the roots of Flueggea virosa. Their structures were established by extensive analyses of spectroscopic data. The isolates were evaluated for anti-HCV activity, as well as the inhibition of superoxide anion generation and elastase release in response to FMLP/cytochalasin B.

Original language	English
Pages (from-to)	447-449
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/j.bmcl.2013.12.051
Publication status	Published - 2014 Jan 15

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/j.bmcl.2013.12.051

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title = "Trinorditerpenes from the roots of Flueggea virosa",

abstract = "Two trinorditerpenes, flueggrenes A and B (1 and 2), have been isolated from the roots of Flueggea virosa. Their structures were established by extensive analyses of spectroscopic data. The isolates were evaluated for anti-HCV activity, as well as the inhibition of superoxide anion generation and elastase release in response to FMLP/cytochalasin B.",

author = "Chao, {Chih Hua} and Cheng, {Ju Chien} and Hwang, {Tsong Long} and Shen, {De Yang} and Wu, {Tian Shung}",

note = "Funding Information: The authors are grateful for financial support from the National Science Council of Taiwan ( NSC101-2113-M-039-003 ) awarded to C.-H.C. This study was also supported in part by the China Medical University Hospital ( DMR-101-106 ) and China Medical University ( CMU99-S-35 ). ",

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AU - Chao, Chih Hua

AU - Cheng, Ju Chien

AU - Hwang, Tsong Long

AU - Shen, De Yang

AU - Wu, Tian Shung

N1 - Funding Information: The authors are grateful for financial support from the National Science Council of Taiwan ( NSC101-2113-M-039-003 ) awarded to C.-H.C. This study was also supported in part by the China Medical University Hospital ( DMR-101-106 ) and China Medical University ( CMU99-S-35 ).

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Trinorditerpenes from the roots of Flueggea virosa

Abstract

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