Troponin T levels in baboons with pig heterotopic heart transplants

K. Kuwaki, C. Knosalla, F. J.M.F. Dor, B. Gollackner, Yau-Lin Tseng, S. Houser, D. K.C. Cooper

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Troponin T levels have been monitored in baboons (n = 8) undergoing pig heterotopic heart transplantation, and correlated with a decrease in graft contractions and graft survival. Pig heart graft survival was from 12 to 139 days (mean 45, median 33), and graft failure was associated with predominant thrombotic microangiopathy and ischemia, with focal hemorrhage, and edema. An increase in troponin T levels 5 to 6 days before graft failure correlated closely with diminished graft contractions. An increase in troponin T was a reliable indicator that graft dysfunction was occurring.

Original languageEnglish
Pages (from-to)92-94
Number of pages3
JournalJournal of Heart and Lung Transplantation
Volume24
Issue number1
DOIs
Publication statusPublished - 2005 Jan 1

Fingerprint

Troponin T
Papio
Swine
Transplants
Graft Survival
Heterotopic Transplantation
Thrombotic Microangiopathies
Heart Transplantation
Edema
Ischemia
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

Cite this

Kuwaki, K., Knosalla, C., Dor, F. J. M. F., Gollackner, B., Tseng, Y-L., Houser, S., & Cooper, D. K. C. (2005). Troponin T levels in baboons with pig heterotopic heart transplants. Journal of Heart and Lung Transplantation, 24(1), 92-94. https://doi.org/10.1016/j.healun.2003.09.039
Kuwaki, K. ; Knosalla, C. ; Dor, F. J.M.F. ; Gollackner, B. ; Tseng, Yau-Lin ; Houser, S. ; Cooper, D. K.C. / Troponin T levels in baboons with pig heterotopic heart transplants. In: Journal of Heart and Lung Transplantation. 2005 ; Vol. 24, No. 1. pp. 92-94.
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Kuwaki, K, Knosalla, C, Dor, FJMF, Gollackner, B, Tseng, Y-L, Houser, S & Cooper, DKC 2005, 'Troponin T levels in baboons with pig heterotopic heart transplants', Journal of Heart and Lung Transplantation, vol. 24, no. 1, pp. 92-94. https://doi.org/10.1016/j.healun.2003.09.039

Troponin T levels in baboons with pig heterotopic heart transplants. / Kuwaki, K.; Knosalla, C.; Dor, F. J.M.F.; Gollackner, B.; Tseng, Yau-Lin; Houser, S.; Cooper, D. K.C.

In: Journal of Heart and Lung Transplantation, Vol. 24, No. 1, 01.01.2005, p. 92-94.

Research output: Contribution to journalArticle

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AU - Tseng, Yau-Lin

AU - Houser, S.

AU - Cooper, D. K.C.

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AB - Troponin T levels have been monitored in baboons (n = 8) undergoing pig heterotopic heart transplantation, and correlated with a decrease in graft contractions and graft survival. Pig heart graft survival was from 12 to 139 days (mean 45, median 33), and graft failure was associated with predominant thrombotic microangiopathy and ischemia, with focal hemorrhage, and edema. An increase in troponin T levels 5 to 6 days before graft failure correlated closely with diminished graft contractions. An increase in troponin T was a reliable indicator that graft dysfunction was occurring.

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