Tubular polyvinyl alcohol composites used as vascular grafts

Manufacturing techniques and property evaluations

Jia Horng Lin, Jin-Jia Hu, Cheng Ying Tu, Mong Chuan Lee, Chao Tsang Lu, Po Ching Lu, Yueh Sheng Chen, Ching Wen Lou

Research output: Contribution to journalArticle

Abstract

This study aims at developing biodegradable vascular grafts by combining PVA knits and porous polyvinyl alcohol PVA hydrogels. The proposed tubular PVA composites are compared to the commercially available vascular grafts in terms of compliance that best matches the compliance of natural vessels. The warp knits and weft knits are first evaluated for their circumferential properties, while the hydrogels are examined for their porous structure. The tubular PVA composites containing knits and hydrogels are then tested for variations in their diameter and compliance. The results indicate that the weft knits exhibit greater circumferential deformation. Moreover, vascular grafts composed of weft knits also have a higher porous connectivity and compliance that matches native vessels.

Original languageEnglish
Pages (from-to)201-204
Number of pages4
JournalMaterials Letters
Volume190
DOIs
Publication statusPublished - 2017 Mar 1

Fingerprint

Polyvinyl Alcohol
polyvinyl alcohol
Polyvinyl alcohols
Grafts
Hydrogels
vessels
manufacturing
composite materials
evaluation
Composite materials
Compliance

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Lin, Jia Horng ; Hu, Jin-Jia ; Tu, Cheng Ying ; Lee, Mong Chuan ; Lu, Chao Tsang ; Lu, Po Ching ; Chen, Yueh Sheng ; Lou, Ching Wen. / Tubular polyvinyl alcohol composites used as vascular grafts : Manufacturing techniques and property evaluations. In: Materials Letters. 2017 ; Vol. 190. pp. 201-204.
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Tubular polyvinyl alcohol composites used as vascular grafts : Manufacturing techniques and property evaluations. / Lin, Jia Horng; Hu, Jin-Jia; Tu, Cheng Ying; Lee, Mong Chuan; Lu, Chao Tsang; Lu, Po Ching; Chen, Yueh Sheng; Lou, Ching Wen.

In: Materials Letters, Vol. 190, 01.03.2017, p. 201-204.

Research output: Contribution to journalArticle

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AU - Lin, Jia Horng

AU - Hu, Jin-Jia

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AU - Lee, Mong Chuan

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AU - Lu, Po Ching

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AU - Lou, Ching Wen

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AB - This study aims at developing biodegradable vascular grafts by combining PVA knits and porous polyvinyl alcohol PVA hydrogels. The proposed tubular PVA composites are compared to the commercially available vascular grafts in terms of compliance that best matches the compliance of natural vessels. The warp knits and weft knits are first evaluated for their circumferential properties, while the hydrogels are examined for their porous structure. The tubular PVA composites containing knits and hydrogels are then tested for variations in their diameter and compliance. The results indicate that the weft knits exhibit greater circumferential deformation. Moreover, vascular grafts composed of weft knits also have a higher porous connectivity and compliance that matches native vessels.

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