TY - JOUR
T1 - Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy
AU - Chen, Kao Ching
AU - Yang, Yen Kuang
AU - Chen, Po See
AU - Yeh, Tzung Lieh
AU - Yang, Ming Jen
PY - 2003/8
Y1 - 2003/8
N2 - The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate, and benzodiazepine. Two cases of hypothermia occurred after combining the use of zotepine, valproate, and benzodiazepine. The valproate was under therapeutic blood level when zotepine dosage was raised to 200 mg/day, and hypothermia occurred. The dosage of zotepine might constitute a positive correlation with hypothermia. The combination of zotepine, valproate or benzodiazepine may cause hypothermia as a side-effect.
AB - The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate, and benzodiazepine. Two cases of hypothermia occurred after combining the use of zotepine, valproate, and benzodiazepine. The valproate was under therapeutic blood level when zotepine dosage was raised to 200 mg/day, and hypothermia occurred. The dosage of zotepine might constitute a positive correlation with hypothermia. The combination of zotepine, valproate or benzodiazepine may cause hypothermia as a side-effect.
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U2 - 10.1046/j.1440-1819.2003.01133.x
DO - 10.1046/j.1440-1819.2003.01133.x
M3 - Article
C2 - 12839516
AN - SCOPUS:0041654621
VL - 57
SP - 369
EP - 371
JO - Psychiatry and Clinical Neurosciences
JF - Psychiatry and Clinical Neurosciences
SN - 1323-1316
IS - 4
ER -
