Two cases of interleukin-7-deficient generalized verrucosis

Hideyuki Kosumi; Ken Natsuga; Shota Takashima; Toshinari Miyauchi; Yi Ting Huang; Toshifumi Nomura; Teruki Yanagi; Hsin Yu Huang; Frank Po Chao Chiu; Peng Chieh Chen; Chao Kai Hsu; Hiroshi Shimizu

doi:10.1093/cid/ciz1240

Two cases of interleukin-7-deficient generalized verrucosis

Hideyuki Kosumi, Ken Natsuga, Shota Takashima, Toshinari Miyauchi, Yi Ting Huang, Toshifumi Nomura, Teruki Yanagi, Hsin Yu Huang, Frank Po Chao Chiu, Peng Chieh Chen, Chao Kai Hsu, Hiroshi Shimizu

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

We report 2 generalized verrucosis (GV) patients homozygous for a novel mutation in the start codon of IL7. Unlike the previous report in which IL-7 deficiency accompanied CD4 T lymphocytopenia, circulating CD4 T cells were not depleted in one of our patients, suggesting a GV pathogenesis other than poor T-cell development.

Original language	English
Pages (from-to)	1561-1563
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	71
Issue number	6
DOIs	https://doi.org/10.1093/cid/ciz1240
Publication status	Published - 2020 Sept 15

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/cid/ciz1240

Cite this

@article{eae647f0a3b34f759633d15572b68a18,

title = "Two cases of interleukin-7-deficient generalized verrucosis",

abstract = "We report 2 generalized verrucosis (GV) patients homozygous for a novel mutation in the start codon of IL7. Unlike the previous report in which IL-7 deficiency accompanied CD4 T lymphocytopenia, circulating CD4 T cells were not depleted in one of our patients, suggesting a GV pathogenesis other than poor T-cell development.",

author = "Hideyuki Kosumi and Ken Natsuga and Shota Takashima and Toshinari Miyauchi and Huang, {Yi Ting} and Toshifumi Nomura and Teruki Yanagi and Huang, {Hsin Yu} and Chiu, {Frank Po Chao} and Chen, {Peng Chieh} and Hsu, {Chao Kai} and Hiroshi Shimizu",

year = "2020",

month = sep,

day = "15",

doi = "10.1093/cid/ciz1240",

language = "English",

volume = "71",

pages = "1561--1563",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

number = "6",

}

TY - JOUR

T1 - Two cases of interleukin-7-deficient generalized verrucosis

AU - Kosumi, Hideyuki

AU - Natsuga, Ken

AU - Takashima, Shota

AU - Miyauchi, Toshinari

AU - Huang, Yi Ting

AU - Nomura, Toshifumi

AU - Yanagi, Teruki

AU - Huang, Hsin Yu

AU - Chiu, Frank Po Chao

AU - Chen, Peng Chieh

AU - Hsu, Chao Kai

AU - Shimizu, Hiroshi

PY - 2020/9/15

Y1 - 2020/9/15

N2 - We report 2 generalized verrucosis (GV) patients homozygous for a novel mutation in the start codon of IL7. Unlike the previous report in which IL-7 deficiency accompanied CD4 T lymphocytopenia, circulating CD4 T cells were not depleted in one of our patients, suggesting a GV pathogenesis other than poor T-cell development.

AB - We report 2 generalized verrucosis (GV) patients homozygous for a novel mutation in the start codon of IL7. Unlike the previous report in which IL-7 deficiency accompanied CD4 T lymphocytopenia, circulating CD4 T cells were not depleted in one of our patients, suggesting a GV pathogenesis other than poor T-cell development.

UR - http://www.scopus.com/inward/record.url?scp=85089875279&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85089875279&partnerID=8YFLogxK

U2 - 10.1093/cid/ciz1240

DO - 10.1093/cid/ciz1240

M3 - Article

C2 - 31900472

AN - SCOPUS:85089875279

SN - 1058-4838

VL - 71

SP - 1561

EP - 1563

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 6

ER -

Two cases of interleukin-7-deficient generalized verrucosis

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this