Two isoquinolones from the roots of phellodendron amurense var. wilsonii

Yu Lung Chiang; Chung Ren Su; Ping Chung Kuo; Amooru G. Damu; Tian Shung Wu

doi:10.3987/COM-05-10598

Two isoquinolones from the roots of phellodendron amurense var. wilsonii

Yu Lung Chiang, Chung Ren Su, Ping Chung Kuo, Amooru G. Damu, Tian Shung Wu

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Two isoquinolones, anhydroberberillic acid (1) and methyl anhydroberberillate (2) were isolated first time from the roots of Phellodendron amurense var. wilsonii as well as two related known compounds, berberine (3) and 8-oxyberberine (4). Their structures were elucidated by extensive 1D, 2D NMR and MS spectral analysis. Occurrence of the isoquinolones and protoberberines in the same plant indicated the definite possibility of these metabolites biogenetically originated from berberine alkaloids.

Original language	English
Pages (from-to)	339-345
Number of pages	7
Journal	Heterocycles
Volume	68
Issue number	2
DOIs	https://doi.org/10.3987/COM-05-10598
Publication status	Published - 2006 Feb 1

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Pharmacology
Organic Chemistry

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abstract = "Two isoquinolones, anhydroberberillic acid (1) and methyl anhydroberberillate (2) were isolated first time from the roots of Phellodendron amurense var. wilsonii as well as two related known compounds, berberine (3) and 8-oxyberberine (4). Their structures were elucidated by extensive 1D, 2D NMR and MS spectral analysis. Occurrence of the isoquinolones and protoberberines in the same plant indicated the definite possibility of these metabolites biogenetically originated from berberine alkaloids.",

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AU - Chiang, Yu Lung

AU - Su, Chung Ren

AU - Kuo, Ping Chung

AU - Damu, Amooru G.

AU - Wu, Tian Shung

PY - 2006/2/1

Y1 - 2006/2/1

N2 - Two isoquinolones, anhydroberberillic acid (1) and methyl anhydroberberillate (2) were isolated first time from the roots of Phellodendron amurense var. wilsonii as well as two related known compounds, berberine (3) and 8-oxyberberine (4). Their structures were elucidated by extensive 1D, 2D NMR and MS spectral analysis. Occurrence of the isoquinolones and protoberberines in the same plant indicated the definite possibility of these metabolites biogenetically originated from berberine alkaloids.

AB - Two isoquinolones, anhydroberberillic acid (1) and methyl anhydroberberillate (2) were isolated first time from the roots of Phellodendron amurense var. wilsonii as well as two related known compounds, berberine (3) and 8-oxyberberine (4). Their structures were elucidated by extensive 1D, 2D NMR and MS spectral analysis. Occurrence of the isoquinolones and protoberberines in the same plant indicated the definite possibility of these metabolites biogenetically originated from berberine alkaloids.

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Two isoquinolones from the roots of phellodendron amurense var. wilsonii

Abstract

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