Two isoquinolones from the roots of phellodendron amurense var. wilsonii

Yu Lung Chiang, Chung Ren Su, Ping Chung Kuo, Amooru G. Damu, Tian Shung Wu

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Two isoquinolones, anhydroberberillic acid (1) and methyl anhydroberberillate (2) were isolated first time from the roots of Phellodendron amurense var. wilsonii as well as two related known compounds, berberine (3) and 8-oxyberberine (4). Their structures were elucidated by extensive 1D, 2D NMR and MS spectral analysis. Occurrence of the isoquinolones and protoberberines in the same plant indicated the definite possibility of these metabolites biogenetically originated from berberine alkaloids.

Original languageEnglish
Pages (from-to)339-345
Number of pages7
Issue number2
Publication statusPublished - 2006 Feb 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry


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