Ultrasonography for Diagnosing Carpal Tunnel Syndrome: A Meta-Analysis of Diagnostic Test Accuracy

Ta-Wei Tai, Cheng Yi Wu, Fong-chin Su, Tai Chang Chern, I. Ming Jou

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

Ultrasonography is widely used to diagnose carpal tunnel syndrome (CTS), a common peripheral neuropathy, but the reported diagnostic accuracy varies. This meta-analysis focused on the diagnostic test accuracy of ultrasonography for diagnosing CTS. Structured searches of PubMed for 1990-2010 were done and the data were extracted and meta-analyzed by pooling estimates of sensitivity, specificity, likelihood ratios and diagnostic odds ratios. Diagnostic performance was also judged by using a summary receiver operating characteristic curve. Twenty-eight trials involving 3995 wrists were included. A greater cross-sectional area (CSA) of the median nerve at the carpal tunnel inlet (CSA-I) and a greater flattening ratio at the level of the hamate were seen in CTS wrists than in control wrists. A CSA-I ≥9 mm 2 is the best single diagnostic criterion, with a diagnostic odds ratio of 40.4 (sensitivity 87.3%, specificity 83.3%).

Original languageEnglish
Pages (from-to)1121-1128
Number of pages8
JournalUltrasound in Medicine and Biology
Volume38
Issue number7
DOIs
Publication statusPublished - 2012 Jul 1

Fingerprint

Carpal Tunnel Syndrome
wrist
Wrist
Routine Diagnostic Tests
tunnels
Meta-Analysis
Ultrasonography
Odds Ratio
Sensitivity and Specificity
likelihood ratio
Median Nerve
sensitivity
nerves
Peripheral Nervous System Diseases
flattening
PubMed
ROC Curve
receivers
curves
estimates

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Biophysics

Cite this

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Ultrasonography for Diagnosing Carpal Tunnel Syndrome : A Meta-Analysis of Diagnostic Test Accuracy. / Tai, Ta-Wei; Wu, Cheng Yi; Su, Fong-chin; Chern, Tai Chang; Jou, I. Ming.

In: Ultrasound in Medicine and Biology, Vol. 38, No. 7, 01.07.2012, p. 1121-1128.

Research output: Contribution to journalArticle

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