It is unknown whether inorganic arsenic in drinking water concentrations at the current maximum contaminant level of 50 μg/l poses a cancer risk in the United States. Data from two large epidemiological studies of cancer and arsenic in drinking water in Taiwan indicate a dose-response relationship, but the magnitude of risk at low concentrations is highly uncertain. Four sources of uncertainty are described: model choice, data aggregation, intra-village variability of arsenic in well water, arsenic intake from food. New data from an appropriately designed epidemiological study are needed to improve dose-response assessment.
All Science Journal Classification (ASJC) codes
- Ecological Modelling
- Health, Toxicology and Mutagenesis