Unusual stilbenoids and a stilbenolignan from seeds of Syagrus romanzoffiana

Sio-Hong Lam, Shoei Sheng Lee

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Stilbenoids, syagrusins A-B (1-2), and a stilbenolignan, 5-hydroxyaiphanol (3), along with three known phenylpropanoids (4-6), were isolated from seeds of Syagrus romanzoffiana. Compounds 1 and 2 possess unusual 1,4,4a,9a-tetrahydrofluoren-9-one and bicyclo[3.3.0]octanedione skeletons, respectively, whereas compound 3 is a stilbenolignan belonging to a very rare structural class of plant secondary metabolites. Their structures were elucidated by spectroscopic analyses. Compounds 1-3 exhibited moderate inhibitory activity against α-glucosidase with IC50 values of 16.9 μM (1), 23.7 μM (2) and 12.8 μM (3), respectively.

Original languageEnglish
Pages (from-to)792-797
Number of pages6
JournalPhytochemistry
Volume71
Issue number7
DOIs
Publication statusPublished - 2010 May 1

Fingerprint

Syagrus romanzoffiana
stilbenoids
Glucosidases
glucosidases
phenylpropanoids
Metabolites
Skeleton
secondary metabolites
Inhibitory Concentration 50
skeleton
inhibitory concentration 50
Seed
Seeds
seeds

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

Cite this

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abstract = "Stilbenoids, syagrusins A-B (1-2), and a stilbenolignan, 5-hydroxyaiphanol (3), along with three known phenylpropanoids (4-6), were isolated from seeds of Syagrus romanzoffiana. Compounds 1 and 2 possess unusual 1,4,4a,9a-tetrahydrofluoren-9-one and bicyclo[3.3.0]octanedione skeletons, respectively, whereas compound 3 is a stilbenolignan belonging to a very rare structural class of plant secondary metabolites. Their structures were elucidated by spectroscopic analyses. Compounds 1-3 exhibited moderate inhibitory activity against α-glucosidase with IC50 values of 16.9 μM (1), 23.7 μM (2) and 12.8 μM (3), respectively.",
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Unusual stilbenoids and a stilbenolignan from seeds of Syagrus romanzoffiana. / Lam, Sio-Hong; Lee, Shoei Sheng.

In: Phytochemistry, Vol. 71, No. 7, 01.05.2010, p. 792-797.

Research output: Contribution to journalArticle

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