Unusual stilbenoids and a stilbenolignan from seeds of Syagrus romanzoffiana

Sio Hong Lam; Shoei Sheng Lee

doi:10.1016/j.phytochem.2010.01.013

Unusual stilbenoids and a stilbenolignan from seeds of Syagrus romanzoffiana

Sio Hong Lam, Shoei Sheng Lee

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Stilbenoids, syagrusins A-B (1-2), and a stilbenolignan, 5-hydroxyaiphanol (3), along with three known phenylpropanoids (4-6), were isolated from seeds of Syagrus romanzoffiana. Compounds 1 and 2 possess unusual 1,4,4a,9a-tetrahydrofluoren-9-one and bicyclo[3.3.0]octanedione skeletons, respectively, whereas compound 3 is a stilbenolignan belonging to a very rare structural class of plant secondary metabolites. Their structures were elucidated by spectroscopic analyses. Compounds 1-3 exhibited moderate inhibitory activity against α-glucosidase with IC₅₀ values of 16.9 μM (1), 23.7 μM (2) and 12.8 μM (3), respectively.

Original language	English
Pages (from-to)	792-797
Number of pages	6
Journal	Phytochemistry
Volume	71
Issue number	7
DOIs	https://doi.org/10.1016/j.phytochem.2010.01.013
Publication status	Published - 2010 May 1

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Plant Science
Horticulture

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title = "Unusual stilbenoids and a stilbenolignan from seeds of Syagrus romanzoffiana",

abstract = "Stilbenoids, syagrusins A-B (1-2), and a stilbenolignan, 5-hydroxyaiphanol (3), along with three known phenylpropanoids (4-6), were isolated from seeds of Syagrus romanzoffiana. Compounds 1 and 2 possess unusual 1,4,4a,9a-tetrahydrofluoren-9-one and bicyclo[3.3.0]octanedione skeletons, respectively, whereas compound 3 is a stilbenolignan belonging to a very rare structural class of plant secondary metabolites. Their structures were elucidated by spectroscopic analyses. Compounds 1-3 exhibited moderate inhibitory activity against α-glucosidase with IC50 values of 16.9 μM (1), 23.7 μM (2) and 12.8 μM (3), respectively.",

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N2 - Stilbenoids, syagrusins A-B (1-2), and a stilbenolignan, 5-hydroxyaiphanol (3), along with three known phenylpropanoids (4-6), were isolated from seeds of Syagrus romanzoffiana. Compounds 1 and 2 possess unusual 1,4,4a,9a-tetrahydrofluoren-9-one and bicyclo[3.3.0]octanedione skeletons, respectively, whereas compound 3 is a stilbenolignan belonging to a very rare structural class of plant secondary metabolites. Their structures were elucidated by spectroscopic analyses. Compounds 1-3 exhibited moderate inhibitory activity against α-glucosidase with IC50 values of 16.9 μM (1), 23.7 μM (2) and 12.8 μM (3), respectively.

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