Urolithiasis Is a Risk Factor for Uroseptic Shock and Acute Kidney Injury in Patients With Urinary Tract Infection

Chih Yen Hsiao, Tsung Hsien Chen, Yi Chien Lee, Meng Chang Hsiao, Peir Haur Hung, Yih Yuan Chen, Ming Cheng Wang

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4 Citations (Scopus)

Abstract

Urinary tract infection (UTI) is a common complication in patients with urolithiasis. This study aimed to compare clinical manifestations and treatment outcomes among UTI patients with or without urolithiasis. It also focused on identifying relationships among urolithiasis, uroseptic shock, and acute kidney injury (AKI). This retrospective study enrolled hospitalized UTI patients who underwent imaging in an acute care setting from January 2006 to March 2015. Of 662 participants enrolled, 113 (17.1%) had urolithiasis, 107 (16.2%) developed uroseptic shock, and 184 (27.8%) developed AKI. A multivariate logistic regression analysis showed that in UTI patients, urolithiasis is associated with an increased risk of uroseptic shock (OR 1.80, 95% CI: 1.08–3.02, P = 0.025), AKI (OR 1.95, 95% CI: 1.22–3.12, P = 0.005), and bacteremia (OR 1.68, 95% CI: 1.08–2.64, P = 0.022). Urolithiasis is common in UTI patients and is associated with an increased risk of uroseptic shock and AKI.

Original languageEnglish
Article number288
JournalFrontiers in Medicine
Volume6
DOIs
Publication statusPublished - 2019 Dec 5

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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